A Case Control Study of Sensory Nerve Conduction in Hypothyroidism


Authors : Syam Mohan; Sangeeta Singhal; Anjum Mirza Chughtai

Volume/Issue : Volume 7 - 2022, Issue 4 - April

Google Scholar : https://bit.ly/3IIfn9N

Scribd : https://bit.ly/3M81ynE

DOI : https://doi.org/10.5281/zenodo.6535940

Thyroid hormones (TH) are having significant effects on the nervous system. They are important for the development of Central Nervous System and myelination of neurons. Thyroid diseases can lead to neuromuscular dysfunction. Materials and Methods:The study was conducted in the department of Physiology and department of Medicine in J N Medical College, Aligarh. 50 patients with hypothyroidism were included in the study. The diagnosis of hypothyroidism was confirmed by serum TSH levels. They were then sent for nerve conduction study of Ulnar, Median and Sural nerve. Results: There were significant changes in the latency, amplitude and conduction velocity in the sensory nerve conduction study of Ulnar, Median and Sural nerve on both sides. Conclusion: Hypothyroidism manifests as polyneuropathy which is mixed type. There is the involvement of nerves in both upper and lower limbs which can be diagnosed even before the occurrence of other clinical symptoms in hypothyroidism. There is a need to include sensory nerve conduction in the initial workup of hypothyroid patients.

Keywords : Sensory, Nerve conduction, Hypothyroidism, Polyneuropathy.

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