A chronic, progressive bone illness with an
unknown aetiology, Paget disease of bone (PDB) causes
excessive, disorganised bone growth that results in pain,
fractures, and deformities. It starts out by increasing bone
resorption. Both monostotic and polyostotic illness
manifestations are possible. The Anglo-Saxon population
has a high prevalence of PDB, yet In India, they are not
common. The condition is frequently asymptomatic and is
prevalent in elderly populations. The majority of the time,
radiographic analysis and biochemical indicators of bone
turnover are used to determine the disease's diagnosis.
While calcium and phosphate levels are normally within
normal ranges, markedly increased serum alkaline
phosphatase (SAP) is a frequent feature. We disclose a
case of a 65-year-old male patient with maxillary-
mandibular involvement. Although PD is frequently seen
in western nations, it is uncommon in Asian populations.
Keywords : Cotton wool appearance, leontiasis ossea, Paget’s disease of bone, serum alkaline phosphatase, Bone disease, bone turnover, osteitis deformans.