A Case Report of Paget's Disease of Bone Involving Maxilla and Mandible: A Diagnostic Dilemma


Authors : Dr. Arti Saluja Sachdev; Dr. Taseer Bashir; Dr. Arpan Manna; Dr. M. K. Sunil; Dr. Ahmed Mohammed Saaduddin Sapri; Dr Naeem Ahmad

Volume/Issue : Volume 8 - 2023, Issue 7 - July

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://tinyurl.com/ykvzmbcb

DOI : https://doi.org/10.5281/zenodo.8198459

A chronic, progressive bone illness with an unknown aetiology, Paget disease of bone (PDB) causes excessive, disorganised bone growth that results in pain, fractures, and deformities. It starts out by increasing bone resorption. Both monostotic and polyostotic illness manifestations are possible. The Anglo-Saxon population has a high prevalence of PDB, yet In India, they are not common. The condition is frequently asymptomatic and is prevalent in elderly populations. The majority of the time, radiographic analysis and biochemical indicators of bone turnover are used to determine the disease's diagnosis. While calcium and phosphate levels are normally within normal ranges, markedly increased serum alkaline phosphatase (SAP) is a frequent feature. We disclose a case of a 65-year-old male patient with maxillary- mandibular involvement. Although PD is frequently seen in western nations, it is uncommon in Asian populations.

Keywords : Cotton wool appearance, leontiasis ossea, Paget’s disease of bone, serum alkaline phosphatase, Bone disease, bone turnover, osteitis deformans.

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