Authors :
Zuha Shariff; Dr. T. Vithya; Dr. Shankar Prasad
Volume/Issue :
Volume 8 - 2023, Issue 8 - August
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/yc5wxdhd
DOI :
https://doi.org/10.5281/zenodo.8269088
Abstract :
Faropenem, an orally active Carbapenem,
showcases a distinctive molecular structure characterized
by a beta-lactam ring accompanied by a chiral
tetrahydrofuran substitution at the C2 position. This
structural modification serves a dual purpose: it enhances
the compound's chemical stability while also diminishing
the potential for adverse effects within the central
nervous system (CNS) [1]. Consequently, Faropenem
emerges as a notably safer therapeutic choice in
comparison to other compounds within its
pharmacological class. However, it is essential to highlight
that the current body of literature remains notably
lacking in substantial evidence linking Faropenem usage
to triggering of seizures. In light of this, we present a case
report featuring a 48-year-old woman who, subsequent to
receiving the Faropenem antibiotic, presented with a
series of recurrent focal seizures.
Keywords :
Adverse Drug Reaction; Carbapenem; Faropenem; Seizure.
Faropenem, an orally active Carbapenem,
showcases a distinctive molecular structure characterized
by a beta-lactam ring accompanied by a chiral
tetrahydrofuran substitution at the C2 position. This
structural modification serves a dual purpose: it enhances
the compound's chemical stability while also diminishing
the potential for adverse effects within the central
nervous system (CNS) [1]. Consequently, Faropenem
emerges as a notably safer therapeutic choice in
comparison to other compounds within its
pharmacological class. However, it is essential to highlight
that the current body of literature remains notably
lacking in substantial evidence linking Faropenem usage
to triggering of seizures. In light of this, we present a case
report featuring a 48-year-old woman who, subsequent to
receiving the Faropenem antibiotic, presented with a
series of recurrent focal seizures.
Keywords :
Adverse Drug Reaction; Carbapenem; Faropenem; Seizure.
