Severe hyponatremia due to hypopituitarism and
adrenal insufficiency can be life threatening and
treatment with glucocorticoids is very effective once the
diagnosis of the underlying disorder has been made. In
our experience, the diagnosis of hypopituitarism in
hyponatremic patients is often overlooked.
We report the case of a 54 year old female
admitted to our hospital in an obtunded state with
altered sensorium. We found that a severe
hyponatremia was the cause of patient condition .
Previously she was diagnosed with recurrent episodes of
hyponatremia leading to encephalopathy. The diagnosis
of hypopituitarism is often overlooked in hyponatremic
patients. Hyponatremia should always be ruled out for
Our study concludes that hyponatremia is due to
hypopituitarism that is secondary to adrenal
insufficiency leading to encephalopathy.
Keywords : Hyponatremia; postpartum hypopituitarism; secondary to adrenal insufficiency; metabolic encephalopathy.