Authors : Ranjan K; Dr. Satish S; Ananya; Shibla Sahin; Fathimath Rifna; Aswathy R S

Volume/Issue : Volume 10 - 2025, Issue 6 - June

Google Scholar : https://tinyurl.com/yruwvc6w

DOI : https://doi.org/10.38124/ijisrt/25jun1602

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Abstract : The present study was aimed to asses the knowledge, attitude and practice in handling ADR, to find the reason behind under-reporting of ADR, to educate community about importance of ADR reporting and also to analyse the impact of education on ADR reporting. A survey-based study was conducted for a period of 6 months among the general public of Dakshina Kannada. A total of 300 participants were completed the questionnaire and participate in the study. Based on knowledge participants were scored and score <6 (150) were grouped as intervention group further they were subcategorized as control and treatment 75 each. Intervention study was carried using PIL and video after the interval of 1 month re- administered same questionnaire to check the impact pharmacist intervention regarding ADR and its management. Majority (68%) of the participants were unaware about the term ADR, 31% believe that all the drugs available in the market are safe, 28.6% were unsure where to report ADR. Although 79.66% of the participants believe that ADR is harmful but 95.3% of them have not reported the suspected ADR. When enquiring reasons for not reporting not sure about ADR (65.52%), not sure where to report (11.54%), thinking that ADR reporting is not necessary, legal liability issues and fear of consequences were expressed. After intervention majority 78.66% of the participants were willing to report ADR, there was a significant improvement in the knowledge among the participants regarding ADR and its management was observed. The study concludes that there was a significant improvement in the knowledge among the participants after the intervention and majority of participants were in willing to report ADR but there is a requirement of public sensitization in this regard so the concern authorities need to impose more effort on increasing the public awareness towards the ADR handling through campaigns and public awareness programs, also a brief information about ADR can be included in text books in school level.

Keywords : Adverse Drug Reaction, Public Awareness, Intervention, Patient Information Leaflet (PIL).

References :

1. Ahmad A, Patel I, Balkrishnan R, Mohanta GP, Manna PK. An evaluation of knowledge, attitude and practice of Indian pharmacists towards ADR reporting: A pilot study. Natl Libr Med. 2013;4(4):204–10.
2. Abeijon PG, Costa C, Taracido M, Herdeiro MT, Torre C, Figueiras A. Factors associated with under-reporting of ADR by health care professionals: A systematic review update. Int J Clin Pharm. 2023;46:625–36.
3. Adhikary J, Bhandare B, Adarsh E, Satyanarayana V. A study to assess knowledge, attitude and practice of ADR reporting among physicians in a tertiary care hospital. J Evol Med Dent Sci. 2013;2(9):1027–34.
4. Wang N, Chen Y, Bigi R, Xiang Y, Zhao N, Zhan X, et al. Comparison of public perceptions of ADR reporting and monitoring in eastern and Western China: A cross-sectional study. BMC Health Serv Res. 2022;22:1–11.
5. Gor RAP, Gajjar B, Dalwadi Z, Goyal. Analysis of adverse drug events reported at peripheral ADR Monitoring Centre in Gujarat. Int J Pharm Pharm Sci. 2020;12(6):72–5.
6. Tandon VR, Mahajan V, Khajuria V, Gillani Z. A challenge for pharmacovigilance in India: Under-reporting of adverse drug reactions. Indian J Pharmacol. 2015;47(1):65–71.
7. Sirili N, Kilonzi M, Mwakawanga DL, Mohamedi JA, Thobias JM, Clement A, et al. Awareness, actions, and predictions of actions in ADR reporting among patients attending a referral hospital in Southern Highland Tanzania. Adv Pharmacol Pharm Sci. 2023;23:1–7.
8. Yagadi S, Guguloth RB, Jacob M. Clinical profile of medication-related emergencies among patients presenting to the emergency department: An observational study. J Acute Dis. 2023;12(6):233–7.
9. Ravinandan AP. Drug safety and pharmacovigilance week – an outline. Indian J Pharm Pharmacol. 2022;9(4):205–6.
10. Sales I, Aljadhey H, Albogami Y, Mahmoud MA. Public awareness and perception toward adverse drug reactions reporting in Riyadh, Saudi Arabia. Saudi Pharm J. 2017;25:868–72.
11. Rahman SZ, Khan RA. Is nimesulide safe in a cardiovascular-compromised patient? Indian J Pharmacol. 2004;36(4):252–3.
12. Khan S. Nimesulide and adverse drug reactions: Time for a database. J Postgrad Med. 2008;54:242.
13. Kumar S. Drug linked to child death is still available in India. BMJ. 2003;326:70.
14. Saha K. Use of nimesulide in Indian children must be stopped. BMJ. 2003;326:713.
15. Aljadhey H, Mahmoud MA, et al. Challenges to and the future of medication safety in Saudi Arabia: a qualitative study. Saudi Pharm J. 2014;22(4):326–32.
16. Kalaiselvan V, Prakash J, Singh GN. Pharmacovigilance programme of India. Arch Pharm Pract. 2012;3:229–32.
17. Yu YM, Shin WG, Lee JY, Choi SA, Jo YH, Youn SJ, et al. Patterns of adverse drug reactions in different age groups: Analysis of spontaneous reports by community pharmacists. PLoS One. 2015;10(7):e0132916.
18. Mets M, Volkerts E, Olivier B, Verster J. Effect of hypnotic drugs on body balance and standing steadiness. Sleep Med Rev. 2010;14:259–67.