Authors : Madhuri Sahdev Keskar; Avinash Vasudev Dhobale; Tushar Balasaheb Shinde; Pradip Pralhad Dole; Dhanashree Sharadchandra Kherade; Nita Atamaram Tidke

Volume/Issue : Volume 11 - 2026, Issue 6 - June

Google Scholar : https://tinyurl.com/2sxz9wvp

Scribd : https://tinyurl.com/4v9x49c6

DOI : https://doi.org/10.38124/ijisrt/26jun1969

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Abstract : Microspheres are free-flowing, spherical particulate carriers, ranging from 1 µm to 1000 µm in size, constructed from biodegradable proteins or synthetic polymers. As multiparticulate drug delivery platforms, they are engineered to facilitate sustained or controlled therapeutic release, thereby enhancing drug stability and bioavailability while enabling targeted delivery with predefined kinetics. These systems offer a superior therapeutic alternative to conventional immediate-release dosage forms and provide versatile administration options, including encapsulation in hard gelatin capsules or integration into other delivery platforms. Microspheres encompass a broad spectrum of types—including bioadhesive, magnetic, floating, radioactive, and various polymeric variants—each fabricated through specific, optimized methodologies. Rigorous analytical evaluation is essential to confirm the quality of these systems. This review comprehensively examines the microsphere landscape, detailing their classifications, polymeric constituents, fabrication techniques, characterization, and clinical applications.

Keywords : Microspheres, Types of Microspheres, Microspheres Polymers, Method of Preparation, Characterization, Applications.

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