Authors :
Soumyashreeta Nayak; Kankana Ray Chaudhuri; Shinjini Dasgupta
Volume/Issue :
Volume 7 - 2022, Issue 6 - June
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/39VtdtY
DOI :
https://doi.org/10.5281/zenodo.6767146
Abstract :
Salmonella is a group of rod-shaped bacteria
belonging to the family Enterobacteriaceae. They are
gram-negative and facultatively anaerobic. These bacteria
reside mainly in the intestinal tract of humans and other
animals. The pathogen, Salmonella enterica serovar Typhi
primarily causes typhoid fever, a disease specific to
humans. Salmonella can exist in the human gallbladder in
an asymptomatic carrier state. Salmonella species have the
capability to form biofilms. The production of biofilms
serves as an advantage because bacteria in the biofilm are
resistant to chemical, physical, and mechanical stresses as
well as disinfectants. Biofilm formation also assists in
Salmonella virulence. It is because the bacterial biofilm
serves as a resistant barrier to antibiotics and immune
attacks by the host. This results in a chronic infection
accompanied by the development of Salmonella carrier
state. In this review, we present a comprehensive overview
of Salmonella biofilm formation, factors affecting biofilm
formation, complications arising from biofilm formation,
and available treatments for biofilm-mediated infections.
Keywords :
Salmonella; Biofilm Formation; Gall Bladder; Typhoid; Antibiotic Resistance; Factors; Complication; Treatment.
Salmonella is a group of rod-shaped bacteria
belonging to the family Enterobacteriaceae. They are
gram-negative and facultatively anaerobic. These bacteria
reside mainly in the intestinal tract of humans and other
animals. The pathogen, Salmonella enterica serovar Typhi
primarily causes typhoid fever, a disease specific to
humans. Salmonella can exist in the human gallbladder in
an asymptomatic carrier state. Salmonella species have the
capability to form biofilms. The production of biofilms
serves as an advantage because bacteria in the biofilm are
resistant to chemical, physical, and mechanical stresses as
well as disinfectants. Biofilm formation also assists in
Salmonella virulence. It is because the bacterial biofilm
serves as a resistant barrier to antibiotics and immune
attacks by the host. This results in a chronic infection
accompanied by the development of Salmonella carrier
state. In this review, we present a comprehensive overview
of Salmonella biofilm formation, factors affecting biofilm
formation, complications arising from biofilm formation,
and available treatments for biofilm-mediated infections.
Keywords :
Salmonella; Biofilm Formation; Gall Bladder; Typhoid; Antibiotic Resistance; Factors; Complication; Treatment.
