A Comprehensive Study on Oral Verrucous carcinoma


Authors : Dr. Drishya Dinesh; Dr. Sandhra Maria Sibi; Dr. Kavya C; Dr. Muhsina C H; Dr. Dhanya S Rao; Dr. Raghavendra Kini

Volume/Issue : Volume 10 - 2025, Issue 6 - June


Google Scholar : https://tinyurl.com/cyv4azay

DOI : https://doi.org/10.38124/ijisrt/25jun703

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Oral verrucous carcinoma is a low-grade form of squamous cell carcinoma that commonly appears on the skin and oral mucosa. Clinically, it appears as an ulcer proliferative lesion on the buccal mucosa, further seen on other sites like the gingiva, tongue, and hard palate, or as a proliferative or cauliflower-like lesion [1]. Due to its distinct biologic behaviour, it is a separate entity from oral cavity SCC [2]. VC generally affects people who chew tobacco, smoke, or use snuff. In 1948, Ackerman was the first to define this lesion as a distinct entity [3].

Keywords : Ackermann Tumor, Verrucous Carcinoma.

References :

  1. Keerthi Narayan V. Verrucous Carcinoma of Buccal Mucosa in Female: A Rare Case Report of Traumatic Tooth Origin. Case Rep Dent. 2021 Jun 11;2021:6673038. doi: 10.1155/2021/6673038. PMID: 34194849; PMCID: PMC8214479.
  2. McCoy JM, Waldron CA: Verrucous carcinoma of the oral cavity : a review of 49 cases, Oral Surg 52:623-629,1948.
  3. Ackerman LV: Verrucous carcinoma of the oral cavity,Surgery 23:670-678,1948.
  4. S Malhotra V Raghavan A Kumar A K Singh Verrucos carcinoma on pre-existing oral submucous fibrosisJ Indian Acad Oral Med Radiol2015275937.
  5. MS Greenberg M Glick JA Ship Burket’s Oral Medicine11th ediDecker IncHamilton2008162.
  6. Okubo M, Iwai T, Nakashima H, Koizumi T, Oguri S, Hirota M, Mitsudo K, Tohnai I. Squamous Cell Carcinoma of the Tongue Dorsum: Incidence and Treatment Considerations. Indian J Otolaryngol Head Neck Surg. 2017 Mar;69(1):6-10. doi: 10.1007/s12070-016-0979-z. Epub 2016 May 7. PMID: 28239570; PMCID: PMC5305651.
  7. Dr. K. Balasankari, Dr. E.Sandhiya, Dr. M.Ashwini, Dr. M. Sehtaj, Dr. M. Arunachalam, & Dr. M. Sathish Kumar. (2023). VERRUCOUS CARCINOMA OF LEFT BUCCAL MUCOSA– A CASE REPORT. Journal of Population Therapeutics and Clinical Pharmacology, 30(5), 874-878.
  8. Kallarakkal TG, Ramanathan A, Zain RB. Verrucous papillary lesions: dilemmas in diagnosis and terminology. Int J Dent. 2013;2013:298249. doi: 10.1155/2013/298249. Epub 2013 Sep 24. PMID: 24223590; PMCID: PMC3800582.
  9. Nnko KA, Pima RT, Baraka CJ, Chalya D, Rwakatema DS, Mremi A. Surgical management of a huge oral verrucous carcinoma: A case report and review of the literature. SAGE Open Med Case Rep. 2024 May 22;12:2050313X241252344.: 10.1177/2050313X241252344. PMID: 38784245; PMCID: PMC11113021.
  10. Rao DS, Kalappanavar AN, Ali IM, Annigeri RG. Verrucous carcinoma-an enigma: Case report and review. Contemp Clin Dent. 2016 Jul-Sep;7(3):391-3. doi: 10.4103/0976-237X.188576. PMID: 27630507; PMCID: PMC5004556.
  11. Walvekar RR, Chaukar DA, Deshpande MS, Pai PS, Chaturvedi P, Kakade A. et al. Verrucous carcinoma of the oral cavity: A clinical and pathological study of 101 cases. Oral Oncology 2009; 45: 47– 51.
  12. C Pravda H Srinivasan D Koteeswaran LA Manohar Verrucous carcinoma in association with oral submucous fibrosisIndian J Dent Res201122615.
  13. Clive RE, Ocwieja KM, Karnell LH, Hoyler SS, Seiffert JE, Young JL, et al. A national quality improvement effort: cancer registry data. J Surg Oncol 1995; 58:155–61.
  14. Pulivarthi S, Pachipulusu B, Malligere SB, Govindraju P, T S MK. Ackerman's Tumour - A Case Report. J Clin Diagn Res. 2016 Jan;10(1):ZD08-10. doi: 10.7860/JCDR/2016/13508.7109. Epub 2016 Jan 1. PMID: 26894186; PMCID: PMC4740715.
  15. Wang, Na MDa; Huang, Ming MDb; Lv, Hong MD, PhDc,∗. Head and neck verrucous carcinoma: A population-based analysis of incidence, treatment, and prognosis. Medicine 99(2):p e18660, January 2020. | DOI: 10.1097/MD.0000000000018660.

Oral verrucous carcinoma is a low-grade form of squamous cell carcinoma that commonly appears on the skin and oral mucosa. Clinically, it appears as an ulcer proliferative lesion on the buccal mucosa, further seen on other sites like the gingiva, tongue, and hard palate, or as a proliferative or cauliflower-like lesion [1]. Due to its distinct biologic behaviour, it is a separate entity from oral cavity SCC [2]. VC generally affects people who chew tobacco, smoke, or use snuff. In 1948, Ackerman was the first to define this lesion as a distinct entity [3].

Keywords : Ackermann Tumor, Verrucous Carcinoma.

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