A Cross Over Trial Evaluating Combined Effect of Ruksha Virechana,Lashuna Erandadi Kashaya and Patolamooladi Kashaya in Diagnosed Patients of Non-Alcoholic Steatohepatitis

Authors : Shirvadkar Divyashree M; Dr. Prashanth A S

Volume/Issue : Volume 5 - 2020, Issue 8 - August

Google Scholar : http://bitly.ws/9nMw

Scribd : https://bit.ly/3jUAtWd

DOI : 10.38124/IJISRT20AUG699

The change in living habits due to increasing popularity of fast foods, sedentary lifestyle have given rise to lifestyle disorders and Non Alcoholic Steatohepatitis is one among them. Non Alcoholic Steatohepatitis (NASH) is a spectrum of Non Alcoholic Fatty Liver Disease (NAFLD) characterized by the presence of hepatic steatosis and inflammation with hepatocyte injury (ballooning) with or without fibrosis.There is no direct reference to NASH in Ayurvedic literature but based on the etiopathogenesis, signs and symptoms it can be correlated to Yakritodara.NASH has no FDA approved therapeutics, so, it is need of the hour to search an effective hepatoprotective remedy from Ayurvedic treasure of therapeutics. Hence, the present study was designed as cross over single blind clinical study with the objectives of evaluating the combined efficacy of Amapachana,Ruksha virechana and Shamanoushadhi with Lashuna Erandadi Kashaya and Patolamooladi Kashaya in the management of NASH. Overall study showed marked improvement in 60% of cases and Moderate improvement in 26.66%. Hence,it can be concluded that the combined effect of therapy with Amapachana,Ruksha virechana and Shamanoushadhis (Lashuna Erandadi Kashaya and Patolamooladi Kashaya) has shown a significant role in relieving the signs and symptoms of subjects diagnosed with Non Alcoholic Steatohepatitis

Keywords : Lifestyle disorders,NASH, Yakritodara, Virechana,Lashuna Erandadi Kashaya, Patolamooladi Kashaya.


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