Generally, being a student in Nigeria comes with everyday stressors and harsh realities. For instance, the high frequency at which lecturers go on strikes has sometimes made some students stay in school more than designed. However, Nigerian students also experience other determinants that affect their mental well-being besides these everyday stressors. These determinants include inconsistency of the academic calendar, the harshness of their new environment (particularly new entry students), social problems, gender inequality, poverty, insecurity, and academic calendar instability. This study aimed to present the prevalence and causes of mental disorders among Nigerian university students and thus, propose a new perspective toward preventing mental illness disorders among Nigerian students using a socio-economic model.