Authors :
Moly Thomas; Dr. Rajee Reghunath; Lakshmi G.
Volume/Issue :
Volume 10 - 2025, Issue 12 - December
Google Scholar :
https://tinyurl.com/225t2rhx
Scribd :
https://tinyurl.com/3zarpyau
DOI :
https://doi.org/10.38124/ijisrt/25dec114
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Abstract :
Cancer leads to various health-related hazards to patients, profoundly affecting their quality of life. Breast cancer
is the most common cause of death for women around the world. The diagnosis and treatment of breast cancer may
negatively affect the quality of life of women. This descriptive analytical study is aimed to assess the quality of life in women
with breast cancer who were treated with surgery and chemotherapy.
Objectives
The study is aimed to assess the quality of life among breast cancer patients undergoing chemotherapy and surgical
treatment.
Methods
This descriptive analytical cross sectional study enrolled 45 breast cancer patients who underwent chemotherapy and
surgical procedures, specifically breast-conserving surgery or modified radical mastectomy, between October 17, 2023, and
February 27, 2024.The structured questionnaire gathered clinical and socio demographic information. The Shapiro test
assessed the normality of the data. EORTC QLQC30 and EORTC QLQBR-23 were used to assess the quality of life in breast
cancer patients.
Results
Patients with breast cancer maintain good functional status, with the exception of cognitive functioning. Additionally,
it highlights that these patients are experiencing fatigue, insomnia, appetite loss, constipation, and financial difficulties.
Spearman’s correlation is performed to check the relationship of QoL with other domains of the scale and it is revealed that
domains such as Physical functioning and fatigue are significantly associated with QoL. Independent sample t test, U test
and Kruskal Wallis test are applied to check the demographic and clinical variables associated with QoL domain based on
normality assumptions. Variables ‘support from children’ and ‘total number of support’ were found to be significantly
associated with QoL scale. Patients with breast cancer receiving chemotherapy and surgical treatment have good functional
status, body image, and future perspectives. However, it also reveals that they are experiencing arm symptoms, particularly
difficulty in raising their arms.
Keywords :
Breast Cancer, Quality of Life, Chemotherapy, Mastectomy, Breast Conservation Surgery.
References :
- Sathishkumar K, Chaturvedi M, Das P, Stephen S, Mathur P. Cancer incidence estimates for 2022 & projection for 2025: result from National Cancer Registry Programme, India. Indian journal of medical research. 2022 Oct 1;156(4&5):598-607.
- International Agency for Research on Cancer, World Health Organization. Global Cancer Observatory. Cancer Today; 2023. Accessed February 22, 2023. https://gco.iarc.fr/
- Dhillon PK, Mathur P, Nandakumar A, et al. The burden of cancers and their variations across the states of India: the Global Burden of Disease Study 1990–2016. Lancet Oncol. 2018; 19(10): 1289-1306. doi:10.1016/s1470-2045(18)30447-9
- Cherian K, Acharya NR, Bhargavan RV, Augustine P, Krishnan JK. Quality of life post breast cancer surgery: comparison of breast conservation surgery versus modified radical mastectomy in a developing country. South Asian Journal of Cancer. 2022 Jul;11(03):183-9.
- Fisher B, Anderson S, Bryant J, et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breastcancer. N Engl J Med 2002;347(16):1233-1241
- Litière S, Werutsky G, Fentiman IS, et al. Breast conserving therapy versus mastectomy for stage I-II breast cancer: 20 year follow-up of the EORTC 10801 phase 3 randomised trial. Lancet Oncol 2012;13(04):412–419
- Dubashi B, Vidhubala E, Cyriac S, Sagar TG. Quality of life among younger women with breast cancer: study from a tertiary cancer institute in south India. Indian J Cancer 2010;47(02):142–147 Ho PJ, Gernaat SAM, Hartman M, Verkooijen
- Avis NE, Crawford S, Manuel J. Quality of life among younger women with breast cancer. Journal of Clinical Oncology. 2005 May 20;23(15):3322-30.
- Shoma AM, AM, Mohamed MH, Nouman N, et al. Body image disturbance and surgical decisionmaking in Egyptian post-menopausal breast cancer patients. World J Surg Oncol 2009;7:66. Doi: 10.1186/1477-7819-7-66
- Thomas B, Mohan VN, Thomas I, Pandey M. Development of a distress inventory for cancer: preliminary results. Journal of postgraduate medicine. 2002 Jan 1; 48(1):16.
- Shastri A, Agarwal M, Patel H, Sharma A. A study of quality of life among patients undergoing mastectomy for malignant breast lesions. International Surgery Journal. 2017 Oct 27;4(11):3638-40.
- Safaee A, Moghimi-Dehkordi B, Zeighami B, Tabatabaee HR, Pourhoseingholi MA. Predictors of quality of life in breast cancer patients under chemotherapy. Indian Journal of Cancer. 2008 Jul 1;45(3):107
- Shafaie FS, Mirghafourvand M, Amirzehni J. Predictors of quality of life in patients with breast cancer. Indian journal of palliative care. 2019 Jan;25(1):73.
- Eslamijouybari M, Patidar V, Kumar Mudgal S, Gaur R, Hosseini Marznaki Z, Fournier A, Hossein Hakimi M, Khosravi S. Quality of life, insomnia, attitudes and beliefs in women undergoing chemotherapy for breast cancer: a cross-sectional study in Amol city Northern Iran. BMC Women's Health. 2025 Jul 3;25(1):303.)
Cancer leads to various health-related hazards to patients, profoundly affecting their quality of life. Breast cancer
is the most common cause of death for women around the world. The diagnosis and treatment of breast cancer may
negatively affect the quality of life of women. This descriptive analytical study is aimed to assess the quality of life in women
with breast cancer who were treated with surgery and chemotherapy.
Objectives
The study is aimed to assess the quality of life among breast cancer patients undergoing chemotherapy and surgical
treatment.
Methods
This descriptive analytical cross sectional study enrolled 45 breast cancer patients who underwent chemotherapy and
surgical procedures, specifically breast-conserving surgery or modified radical mastectomy, between October 17, 2023, and
February 27, 2024.The structured questionnaire gathered clinical and socio demographic information. The Shapiro test
assessed the normality of the data. EORTC QLQC30 and EORTC QLQBR-23 were used to assess the quality of life in breast
cancer patients.
Results
Patients with breast cancer maintain good functional status, with the exception of cognitive functioning. Additionally,
it highlights that these patients are experiencing fatigue, insomnia, appetite loss, constipation, and financial difficulties.
Spearman’s correlation is performed to check the relationship of QoL with other domains of the scale and it is revealed that
domains such as Physical functioning and fatigue are significantly associated with QoL. Independent sample t test, U test
and Kruskal Wallis test are applied to check the demographic and clinical variables associated with QoL domain based on
normality assumptions. Variables ‘support from children’ and ‘total number of support’ were found to be significantly
associated with QoL scale. Patients with breast cancer receiving chemotherapy and surgical treatment have good functional
status, body image, and future perspectives. However, it also reveals that they are experiencing arm symptoms, particularly
difficulty in raising their arms.
Keywords :
Breast Cancer, Quality of Life, Chemotherapy, Mastectomy, Breast Conservation Surgery.