A Rare Case of Arnold Chiari – 2 Anomaly


Authors : Dr. Rita D.; Dr. Mounika J.

Volume/Issue : Volume 10 - 2025, Issue 8 - August


Google Scholar : https://tinyurl.com/mrymfub2

Scribd : https://tinyurl.com/5m9mtedz

DOI : https://doi.org/10.38124/ijisrt/25aug452

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Abstract : Introduction: Arnold–Chiari malformations represent structural defects of the hindbrain, first characterized by Austrian pathologist Hans Chiari in the late 19th century. These anomalies involve the posterior cranial fossa and its neural structures, including the cerebellum, pons, and medulla oblongata. Type 2 Chiari malformation is a relatively frequent congenital defect characterized by a beaked midbrain, caudal displacement of the cerebellar tonsils and vermis, and an associated spinal myelomeningocele.  Case Report: We describe an unbooked 20-year-old primigravida presenting at approximately 6 months of amenorrhea with decreased fetal movements and abdominal pain. Antenatal ultrasound revealed lumbosacral spina bifida with features consistent with Arnold–Chiari type 2 malformation. Following counseling, pregnancy termination was performed, and the fetus demonstrated myelomeningocele with hydrocephalus on gross examination.

Keywords : Arnold–Chiari Malformation; Spina Bifida; Primigravida; Congenital Anomaly; Prenatal Diagnosis.

References :

  1. Cunningham FG, Leveno KJ, Bloom SL, Dashe JS, Hoffman BL, Casey BM, et al. Williams Textbook of Obstetrics. 26th ed. New York: McGraw Hill; 2022.
  2. Volpe JJ. Neurology of the Newborn. 6th ed. Philadelphia: Elsevier; 2018.
  3. Hidalgo JA, Tork CA, Varacallo M. Arnold-Chiari Malformation [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan– [updated 2023 Sep 4; cited 2025 Aug 13]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK431076
  4. Valchkevich D, Trifoniuk I, Vorobey H. The Arnold-Chiari Anomaly: A Review of Literature. Am J Biomed Sci Res. 2022;16(1):AJBSR.MS.ID.002193.doi:10.34297/AJBSR.2022.16.002193.
  5. Ganesh D, Sagayaraj BM, Barua RK, Sharma N, Ranga U. Arnold Chiari malformation with spina bifida: a lost opportunity of folic acid supplementation. J Clin Diagn Res. 2014 Dec;8(12):OD01–3. doi:10.7860/JCDR/2014/11242.5335..

Introduction: Arnold–Chiari malformations represent structural defects of the hindbrain, first characterized by Austrian pathologist Hans Chiari in the late 19th century. These anomalies involve the posterior cranial fossa and its neural structures, including the cerebellum, pons, and medulla oblongata. Type 2 Chiari malformation is a relatively frequent congenital defect characterized by a beaked midbrain, caudal displacement of the cerebellar tonsils and vermis, and an associated spinal myelomeningocele.  Case Report: We describe an unbooked 20-year-old primigravida presenting at approximately 6 months of amenorrhea with decreased fetal movements and abdominal pain. Antenatal ultrasound revealed lumbosacral spina bifida with features consistent with Arnold–Chiari type 2 malformation. Following counseling, pregnancy termination was performed, and the fetus demonstrated myelomeningocele with hydrocephalus on gross examination.

Keywords : Arnold–Chiari Malformation; Spina Bifida; Primigravida; Congenital Anomaly; Prenatal Diagnosis.

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Paper Submission Last Date
30 - November - 2025

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