Authors :
Vibisha Victor; Ancy U.; Grace N. Raju; Vipin Venugopalan; Shaiju S. Dharan
Volume/Issue :
Volume 11 - 2026, Issue 9 - September
Google Scholar :
https://tinyurl.com/yc76zwxn
DOI :
https://doi.org/10.38124/ijisrt/26sep398
Note : A published paper may take 4-5
working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and
ResearchGate.
Abstract :
Multiple sclerosis is an autoimmune inflammatory demyelinating process that affects the central nervous system.
It is characterized by inflammatory demyelination and neurodegeneration leading to involvement of the brain, spinal cord,
and optic nerves. Relapsing-remitting multiple sclerosis (RRMS) is the most frequent type of MS and involves recurrent
episodes of neurological dysfunction followed by partial or full recovery. Multifocal involvement of the central nervous
system and numerous brain and spinal cord lesions constitute a difficult clinical condition necessitating early diagnosis and
adequate therapy. A patient of middle age demonstrated signs and symptoms of neurological impairment related to central
nervous system involvement. Brain and spinal cord magnetic resonance imaging (MRI) showed multiple demyelinating
hyperintensive lesions in periventricular, juxtacortical, and infratentorial regions with concomitant spinal cord lesions.
Taking into consideration the pattern and characteristics of the lesions, a diagnosis of multiple sclerosis could be established
in this case. The patient was diagnosed as having relapsing multiple sclerosis. He was prescribed appropriate
immunomodulatory therapy and supportive treatment. In this case, the significance of detecting multifocal demyelinating
lesions in the presence of recurrent neurological manifestations is emphasized. Proper diagnosis based on MRI assessment
and adequate treatment could reduce the number of relapses and the occurrence of neurological disability in the future.
Keywords :
Multiple Sclerosis, Demyelination, CNS Lesions, Spinal Cord Involvement.
References :
- Walton C, King R, Rechtman L, et al. Rising prevalence of multiple sclerosis worldwide: insights from the Atlas of MS. Mult Scler. 2020;26(14):1816-1821.
- Compston A, Coles A. Multiple sclerosis. Lancet. 2008;372(9648):1502-1517.
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Multiple sclerosis is an autoimmune inflammatory demyelinating process that affects the central nervous system.
It is characterized by inflammatory demyelination and neurodegeneration leading to involvement of the brain, spinal cord,
and optic nerves. Relapsing-remitting multiple sclerosis (RRMS) is the most frequent type of MS and involves recurrent
episodes of neurological dysfunction followed by partial or full recovery. Multifocal involvement of the central nervous
system and numerous brain and spinal cord lesions constitute a difficult clinical condition necessitating early diagnosis and
adequate therapy. A patient of middle age demonstrated signs and symptoms of neurological impairment related to central
nervous system involvement. Brain and spinal cord magnetic resonance imaging (MRI) showed multiple demyelinating
hyperintensive lesions in periventricular, juxtacortical, and infratentorial regions with concomitant spinal cord lesions.
Taking into consideration the pattern and characteristics of the lesions, a diagnosis of multiple sclerosis could be established
in this case. The patient was diagnosed as having relapsing multiple sclerosis. He was prescribed appropriate
immunomodulatory therapy and supportive treatment. In this case, the significance of detecting multifocal demyelinating
lesions in the presence of recurrent neurological manifestations is emphasized. Proper diagnosis based on MRI assessment
and adequate treatment could reduce the number of relapses and the occurrence of neurological disability in the future.
Keywords :
Multiple Sclerosis, Demyelination, CNS Lesions, Spinal Cord Involvement.