A Rare Case of Von Willebrand Disease in Pregnancy: Management Strategies and Challenges


Authors : Dr. Asmae Bentaleb; Hounaida Mahfoud; Rim Laaboudi; Mohamed Elkhorassani; Rajae Tachinante; Mounia Yousfi; Fatima Elhasouni

Volume/Issue : Volume 10 - 2025, Issue 8 - August


Google Scholar : https://tinyurl.com/579a2zw6

Scribd : https://tinyurl.com/ycx4su7r

DOI : https://doi.org/10.38124/ijisrt/25aug1024

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Abstract : Von Willebrand disease (VWD), the most common inherited bleeding disorder, is classified into types 1, 2, and 3. Women with VWD are at higher risk of bleeding during menstruation, childbirth, and postpartum. This case of a 24-year-old pregnant woman with VWD underscores the importance of early management to prevent postpartum hemorrhage. Desmopressin and VWF infusion enabled a successful cesarean and uneventful recovery. Diagnosis relies on VWF and FVIII assays, and prophylactic treatment is advised during pregnancy. Vaginal delivery without instrumentation is preferred, with cesarean reserved for obstetric reasons.

Keywords : Von Willebrand Disease, Deficiency, Haemorrhage, Pregnancy.

References :

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Von Willebrand disease (VWD), the most common inherited bleeding disorder, is classified into types 1, 2, and 3. Women with VWD are at higher risk of bleeding during menstruation, childbirth, and postpartum. This case of a 24-year-old pregnant woman with VWD underscores the importance of early management to prevent postpartum hemorrhage. Desmopressin and VWF infusion enabled a successful cesarean and uneventful recovery. Diagnosis relies on VWF and FVIII assays, and prophylactic treatment is advised during pregnancy. Vaginal delivery without instrumentation is preferred, with cesarean reserved for obstetric reasons.

Keywords : Von Willebrand Disease, Deficiency, Haemorrhage, Pregnancy.

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Paper Submission Last Date
30 - November - 2025

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