A Research Article on- Co-Processed Excipients by Preparing Sodium Alginate Microbeads Through Inotropic Gelatin Method


Authors : Dr. Quazi Imaduddin; Shaikh Mohiuddin; Priyanka Kantaram Sonawane; Aashu Sabhapati Yadav

Volume/Issue : Volume 10 - 2025, Issue 7 - July


Google Scholar : https://tinyurl.com/2nv83e8c

DOI : https://doi.org/10.38124/ijisrt/25jul310

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Abstract : The research article is presented to give complete research and explanation on the development of excipients and microbeads preparation with the help of excipients, and also the approaches involved in similar excipient development. As per the scientist's research, a single element of excipient can’t give the specific or sufficient performance in the production of a product, and also for manufacturing, so they increase the attention on the product by multiplying the excipients in production. They make the production expensive with their cost, production, manufacturing, packaging, etc. The microbeads are small in size, and they are affected in various ways. The microbeads change their colour according to the ingredient used for production.

References :

  1. World journal of pharmaceutical research co processed Excipients article Volume 6, 2017, pg. no. 1-2, by B Mamatha, D. Srilatha
  2. Journal Of Chemical and Pharmaceutical Research, 2021, 13(9):01-10 Sravya K, S Venkateswara Rao, K Padmalatha.
  3. A Review: Co-processed Excipients-An Alternative to Novel Chemical  Entities PD. Chaudhari, AA. Phatak and Ujwala Desai.
  4. Review On Novel Pharmaceutical Co-Processed Excipients, Volume 2, 2019, pg.no 14- 15, by S.B. Pawar, S.P. Ahirrao,S.J. Kshirsagar.
  5. Co-processed Excipients: A Revisit of Its Development In the Past Two Decadesl;A Review, 2022, by Liew Kai Bin, Hii Shou Hui, A.B.M. Helal Uddin, Zaidul Islam Sarker, Chew Yik Ling.
  6. Co-Processed Excipients-A Review, Volume 5, 2020, pg.no 88, by Mukesh Mohite, Sayli Sarnaik, Akshay Lingayat.
  7. Handbook of Pharmaceutical Excipients Fifth Edition, 2006, by LY Galichet, NA Armstrong.
  8. Co- Processed Excipients for Dispersible Tablets –Part 2: Patient Acceptability Karolina Dziemidowicz, Felipe L. Lopez, Ben J. Bowles, Andrew J. Edwards, Terry B. Ernest, Mine Orlu, And Catherine Tuleu.
  9. A review on co-processed excipients used in direct compression of tablet dosage form, 2023,23(01), pg.no. 216-217, by Paka Bhavana and M Sunitha Reddy
  10. A Review on co-processed excipients: Current and future trend of excipients technology, Volume 11,2018, pg.no 7, by Liew Kai Binab, Ananad Gaurav, Uttam Kumar Mandal
  11. Evaluation of co-processed excipients used for direct compression of orally disintegrating tablets (ODT) using novel disintegration apparatus witold brniakl, Renata Jachowiczl, Anna Krupal, Tomasz Skorka, and Krzysztof Niwinski.
  12. Co-processing of small molecule excipients with polymers to improve functionality Prashant kumar K. Parmar, Srilaxmi G. Rao and Arvind K. Bansal
  13. Review on Preparation and Characterization of a Novel Co-Processed Excipients of Chitin and Crystaline Manitol.
  14. Preparation of co-processed excipients for controlled-release of drug assembled with solid lipid Nanoparticles and direct compression materials luis Eduardo serrano-mora, Maria L Zambrano- Zaragoza.
  15. A review on micro beads: Formulation, technological aspects, and extraction GSC Biological and Pharmaceutical Sciences, 2024, 26(02), 059–066 Shaik Khaja Moinuddin, Pradeep Kumar M, Sandeep Kumar G, Perugumi Ramya, Konda Sravya Sree and Kavya K
  16. Diclofenac sodium Microbeads for Oral Sustained Drug Delivery, International journal of Pharmaceutical Technology and Research. 2009; 1(9): 317-327. Manjanna KM, Shivakumar B and Pramodkumar TM.
  17. Formulation and Evaluation of Microbeads for Colon Targeted Drug Delivery Using Natural Polymer by Yashika Uniyal, Manoj Kumar Sarangi and Kriti Dabral wjpmr, 2019,5(7), 153-163

The research article is presented to give complete research and explanation on the development of excipients and microbeads preparation with the help of excipients, and also the approaches involved in similar excipient development. As per the scientist's research, a single element of excipient can’t give the specific or sufficient performance in the production of a product, and also for manufacturing, so they increase the attention on the product by multiplying the excipients in production. They make the production expensive with their cost, production, manufacturing, packaging, etc. The microbeads are small in size, and they are affected in various ways. The microbeads change their colour according to the ingredient used for production.

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Paper Submission Last Date
31 - December - 2025

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