A Review Article on the Emerging Role of Islet Cell Transplantation in Type 1 Diabetes Mellitus


Authors : Dr. Sunkara Surya Lakshmi; Dr. K. Atchuta Kumar; K. Bhargav; D. Sai Shamitha; D. Vineeth Ram

Volume/Issue : Volume 8 - 2023, Issue 11 - November

Google Scholar : https://tinyurl.com/ycy77r6d

Scribd : https://tinyurl.com/39z8y2fk

DOI : https://doi.org/10.5281/zenodo.10282992

Abstract : The metabolic disease known as juvenile diabetes, or Type 1 diabetes is characterized by a reduction in insulin production, which is vital for an individual’s survival. Islet-cell-transplantation is an experimental approach of transferring pancreatic islet cells from donor pancreas to a suitable diabetic patient. Upon implantation the islets begin to produce insulin that is sufficient to maintain blood glucose levels. In this review we discuss what is currently known about pancreatic islet transplantation, its risks and benefits. Based on current evidence, pancreatic islet transplantation appears to be an experimental surgery that is demonstrating promising outcomes for the patients. However, islet transplantation have not been studied comprehensively enough to introduce it as a routine procedure.

The metabolic disease known as juvenile diabetes, or Type 1 diabetes is characterized by a reduction in insulin production, which is vital for an individual’s survival. Islet-cell-transplantation is an experimental approach of transferring pancreatic islet cells from donor pancreas to a suitable diabetic patient. Upon implantation the islets begin to produce insulin that is sufficient to maintain blood glucose levels. In this review we discuss what is currently known about pancreatic islet transplantation, its risks and benefits. Based on current evidence, pancreatic islet transplantation appears to be an experimental surgery that is demonstrating promising outcomes for the patients. However, islet transplantation have not been studied comprehensively enough to introduce it as a routine procedure.

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