Authors :
Gosavi Pallavi A; Somani Shravan J; Rode Abhijit R; Jadhav Akshay S
Volume/Issue :
Volume 8 - 2023, Issue 4 - April
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://bit.ly/3nO5t1X
DOI :
https://doi.org/10.5281/zenodo.7922903
Abstract :
- In 1961, Bangham and his team invented
liposomes, which are concentric bilayer vesicles. They
are quite effective and have a high potential for drug
entrapment. They are the most often employed drug
delivery vehicles due to their size, hydrophobic, and
lipophilic nature. Direct drug delivery to the site of
action is the major goal of this drug delivery system,
which will extend and increase the effects of the
treatment. Both hydrophilic and lipophilic drugs can be
contained inside liposomes, which are biocompatible and
stable. The range of sizes is from 0.05 to 5.0 mm in
diameter. Some conventional methods used for liposomal
manufacturing and size reduction include mechanical
dispersion, solvent dispersion, and detergent removal
techniques. Liposomes can be divided into categories
based on their size, charge, state, and other
characteristics due to variations in the manufacturing
process and lipid composition. A liposome is a drug
delivery system used to administer various types of
medications or active substances, both of which are
necessary for the treatment of various diseases. The
reason a liposome is also known as a targeted drug
delivery system is that it is a very effective drug delivery
system for delivering active medication to a specific area
of the body without entrapping or impacting other areas
of the body. To treat specific diseases, liposomes are
available in a range of sizes to serve as the carrier for
medications or drugs targeted to the active site at a
specific rate and time without damaging other body
parts. Colloidal spheres containing cholesterol, non-toxic
surfactants, sphingolipids, glycolipids, long-chain
unsaturated fats, layer proteins, and active atoms are
also present in this system, which is also known as a
vesicular system. They are an extremely helpful copy,
reagent, and tool in many domains of modern study,
including maths and theoretical physics, biophysics,
chemistry, colloid science, biochemistry, and biology.
Liposomes have since made their way onto the market.
This page gives a general review of liposomes, including
their benefits, drawbacks, mode of action, classification,
structural makeup, preparation, uses, and future
implications.
Keywords :
Liposomes, Classification, Preparation, Mechanism, Purification, Applications.
- In 1961, Bangham and his team invented
liposomes, which are concentric bilayer vesicles. They
are quite effective and have a high potential for drug
entrapment. They are the most often employed drug
delivery vehicles due to their size, hydrophobic, and
lipophilic nature. Direct drug delivery to the site of
action is the major goal of this drug delivery system,
which will extend and increase the effects of the
treatment. Both hydrophilic and lipophilic drugs can be
contained inside liposomes, which are biocompatible and
stable. The range of sizes is from 0.05 to 5.0 mm in
diameter. Some conventional methods used for liposomal
manufacturing and size reduction include mechanical
dispersion, solvent dispersion, and detergent removal
techniques. Liposomes can be divided into categories
based on their size, charge, state, and other
characteristics due to variations in the manufacturing
process and lipid composition. A liposome is a drug
delivery system used to administer various types of
medications or active substances, both of which are
necessary for the treatment of various diseases. The
reason a liposome is also known as a targeted drug
delivery system is that it is a very effective drug delivery
system for delivering active medication to a specific area
of the body without entrapping or impacting other areas
of the body. To treat specific diseases, liposomes are
available in a range of sizes to serve as the carrier for
medications or drugs targeted to the active site at a
specific rate and time without damaging other body
parts. Colloidal spheres containing cholesterol, non-toxic
surfactants, sphingolipids, glycolipids, long-chain
unsaturated fats, layer proteins, and active atoms are
also present in this system, which is also known as a
vesicular system. They are an extremely helpful copy,
reagent, and tool in many domains of modern study,
including maths and theoretical physics, biophysics,
chemistry, colloid science, biochemistry, and biology.
Liposomes have since made their way onto the market.
This page gives a general review of liposomes, including
their benefits, drawbacks, mode of action, classification,
structural makeup, preparation, uses, and future
implications.
Keywords :
Liposomes, Classification, Preparation, Mechanism, Purification, Applications.
