- In 1961, Bangham and his team invented liposomes, which are concentric bilayer vesicles. They are quite effective and have a high potential for drug entrapment. They are the most often employed drug delivery vehicles due to their size, hydrophobic, and lipophilic nature. Direct drug delivery to the site of action is the major goal of this drug delivery system, which will extend and increase the effects of the treatment. Both hydrophilic and lipophilic drugs can be contained inside liposomes, which are biocompatible and stable. The range of sizes is from 0.05 to 5.0 mm in diameter. Some conventional methods used for liposomal manufacturing and size reduction include mechanical dispersion, solvent dispersion, and detergent removal techniques. Liposomes can be divided into categories based on their size, charge, state, and other characteristics due to variations in the manufacturing process and lipid composition. A liposome is a drug delivery system used to administer various types of medications or active substances, both of which are necessary for the treatment of various diseases. The reason a liposome is also known as a targeted drug delivery system is that it is a very effective drug delivery system for delivering active medication to a specific area of the body without entrapping or impacting other areas of the body. To treat specific diseases, liposomes are available in a range of sizes to serve as the carrier for medications or drugs targeted to the active site at a specific rate and time without damaging other body parts. Colloidal spheres containing cholesterol, non-toxic surfactants, sphingolipids, glycolipids, long-chain unsaturated fats, layer proteins, and active atoms are also present in this system, which is also known as a vesicular system. They are an extremely helpful copy, reagent, and tool in many domains of modern study, including maths and theoretical physics, biophysics, chemistry, colloid science, biochemistry, and biology. Liposomes have since made their way onto the market. This page gives a general review of liposomes, including their benefits, drawbacks, mode of action, classification, structural makeup, preparation, uses, and future implications.

Keywords : Liposomes, Classification, Preparation, Mechanism, Purification, Applications.