A Review on Surface Modified Sterically Stabilized Liposomes


Authors : Nihala Nazeer, Jicky T Panicker, Rajalekshmi, S.Mathan, S.D.Shaiju

Volume/Issue : Volume 4 - 2019, Issue 7 - July

Google Scholar : https://goo.gl/DF9R4u

Scribd : https://bit.ly/2YFy236

Liposomes are microvesicles made out of a bilayer of lipid amphipathic molecules, encasing a fluid compartment. The principle constituent of liposomes is phospholipid which contains a hydrophobic tail and hydrophilic head groups which empowers the liposomes to sort out into round bilayer direction in watery media. The hydrophobic tail and hydrophilic head group of the phospholipids is the reason for entrapping both water dissolvable and lipid solvent substances, while staying scattered in the fluid condition. Besides its various points of interest the real restriction in the helpful utilization of customary liposomes upon intravenous organization lies in its quick disposal from the blood and acknowledgment by the reticuloendothelial system (RES). This prompts the improvement of surface changed sterically stabilized liposomes or the stealth liposomes. The nearness of polymers on the outside of liposomes has been appeared to enhance the blood flow time without being effectively perceived by the intrinsic insusceptible framework. This review centers around the development of stealth liposomes, summarizes the generally utilized polymers for the development and finally the applications of this promising innovation.

Keywords : PEG, Stealth Liposomes, Reticulo Endothelial System, Drug Delivery.

CALL FOR PAPERS


Paper Submission Last Date
31 - March - 2024

Paper Review Notification
In 1-2 Days

Paper Publishing
In 2-3 Days

Video Explanation for Published paper

Never miss an update from Papermashup

Get notified about the latest tutorials and downloads.

Subscribe by Email

Get alerts directly into your inbox after each post and stay updated.
Subscribe
OR

Subscribe by RSS

Add our RSS to your feedreader to get regular updates from us.
Subscribe