Authors :
Ali Sharifpour; Babak Mahmoudi; Hossein Saffarfar; Milad Anoushe; Siavash Abedi; Reza Mahmoudi; Payam Ali Khiavi
Volume/Issue :
Volume 9 - 2024, Issue 7 - July
Google Scholar :
https://tinyurl.com/3c8v3c4u
Scribd :
https://shorturl.at/Ku039
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24JUL1387
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Background:
In the recent studies, the relationship between the
magnesium and asthma has been more considered;
hence, the present research has aimed to study this issue.
Methodology:
The study is a Randomized double blind placebo
control trial, which has been conducted on the asthmatic
patients who have been divided into two groups: group
one consisting of those who have taken placebo and
group two including those who have taken magnesium
supplement. In the beginning and during the weeks 4, 8
and 12, FVC, FEV1, FEV1/FVC and ACT score have
been measured.
Results:
40 patients have been studied in two equal groups.
The improvement rate of FEV1/FVC has been gradually
increased in group2 and was significantly higher than
group1 in the week 12. It was also higher in week 4 but
not significantly. Moreover, according to FVC ratio, in
weeks 4 and 12, the cure rate of the group2 was not
significantly higher; however, it was significantly higher
in the 8th week. The ACT score of group2 has also
significantly increased in comparison to it in 4 weeks
before the beginning of the study.
Conclusion:
It seems that the magnesium supplement is helpful
in improving the clinical and spirometric measurements
of asthmatic patients.
Keywords :
Asthma; Magnesium Supplement; Spirometry; ACT Score.
References :
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- Khezerlouy-Aghdam N, Toufan Tabrizi M, Seyed Toutounchi K, Jabbaripour Sarmadian A, Masoumi S. Challenging in pulmonary thromboembolism diagnosis in patients with disproportionate pulmonary hypertension and severe mitral stenosis: Report of two cases. Clin Case Rep. 2024 Mar 7;12(3):e8597. doi: 10.1002/ccr3.8597. PMID: 38464564; PMCID: PMC10920307.
- Safaie N, Masoumi S, Alizadeh S, Mirzajanzadeh P, Nejabati HR, Hajiabbasi M, Alivirdiloo V, Basmenji NC, Derakhshi Radvar A, Majidi Z, Faridvand Y. SGLT2 inhibitors and AMPK: The road to cellular housekeeping? Cell Biochem Funct. 2024 Jan;42(1):e3922. doi: 10.1002/cbf.3922. PMID: 38269506.
- Alivirdiloo V, Hajiabbasi M, Gargari MK, Gargari HK, Ghazi F, Mohammadi M, Rahimi F, Mobed A. Neuroprotective role of nobiletin against amyloid-β (Aβ) aggregation in Parkinson and Alzheimer disease as neurodegenerative diseases of brain. Medicinal Chemistry Research. 2024 Jun 7:1-9.
- Amirabbas Rostami, Torabi, S.M., Masoumi, S. et al. The Crosstalk between Coronary Artery Bypass Grafting and miRNAs. Biol Bull Russ Acad Sci 50, 1167–1171 (2023). https://doi.org/10.1134/S10623 59023602082
- Masoumi S, Separham A, Parizad R, Jafarisis S, Assefi M. Dual Left Anterior Descending Artery: Clinical Overview and Interventional Management. J Tehran Heart Cent. 2023 Apr;18(2):146-150. doi: 10.18502/jthc.v18i2.13326. PMID: 37637287; PMCID: PMC10459347.
- Sheikhnia F, Fazilat A, Rashidi V, Azizzadeh B, Mohammadi M, Maghsoudi H, Majidinia M. Exploring the Therapeutic Potential of Quercetin in Cancer Treatment: Targeting Long Non-Coding RNAs. Pathology-Research and Practice. 2024 May 29:155374.
- Toufan M, Khezerlou-Aghdam N, Masoumi S, Dehghan M, Akhgari A. Biatrial Myxoma with a Shared Stalk: A Case Report. J Tehran Heart Cent. 2021 Oct;16(4):174-177. doi: 10.18502/jthc.v16i4. 8604. PMID: 35935553; PMCID: PMC9308883.
- Toopchizadeh V, Barzegar M, Masoumi S, Jahanjoo F. Prevalence of Vitamin D Deficiency and Associated Risk Factors in Cerebral Palsy A study in North-West of Iran. Iran J Child Neurol. 2018 Spring;12(2):25-32. PMID: 29696043; PMCID: PMC5904735.
Background:
In the recent studies, the relationship between the
magnesium and asthma has been more considered;
hence, the present research has aimed to study this issue.
Methodology:
The study is a Randomized double blind placebo
control trial, which has been conducted on the asthmatic
patients who have been divided into two groups: group
one consisting of those who have taken placebo and
group two including those who have taken magnesium
supplement. In the beginning and during the weeks 4, 8
and 12, FVC, FEV1, FEV1/FVC and ACT score have
been measured.
Results:
40 patients have been studied in two equal groups.
The improvement rate of FEV1/FVC has been gradually
increased in group2 and was significantly higher than
group1 in the week 12. It was also higher in week 4 but
not significantly. Moreover, according to FVC ratio, in
weeks 4 and 12, the cure rate of the group2 was not
significantly higher; however, it was significantly higher
in the 8th week. The ACT score of group2 has also
significantly increased in comparison to it in 4 weeks
before the beginning of the study.
Conclusion:
It seems that the magnesium supplement is helpful
in improving the clinical and spirometric measurements
of asthmatic patients.
Keywords :
Asthma; Magnesium Supplement; Spirometry; ACT Score.