Authors : Aiswarya V. P.; Akhila Elisabath K. B.; Priya Thomas; Reshma James; Shino Thomas; Swetha Anil; Dr. Sr. Prasada K. K.

Volume/Issue : Volume 11 - 2026, Issue 4 - April

Google Scholar : https://tinyurl.com/3ebn2wsf

Scribd : https://tinyurl.com/5h68w7fa

DOI : https://doi.org/10.38124/ijisrt/26apr1688

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Abstract : Human Papilloma virus (HPV) is a leading cause of cervical cancer, yet awareness regarding its vaccination remains limited among young adults. This study aimed to assess the level of knowledge regarding HPV vaccination among undergraduate students and to determine its association with selected demographic variables. A quantitative cross-sectional study was conducted among 190 students using a structured questionnaire. The results revealed that 64% of students had moderate knowledge, 27% had adequate knowledge, and 9% had inadequate knowledge. A significant association was found between knowledge level and age as well as lifestyle (p < 0.05), while no significant association was observed with other variables. The study concludes that knowledge regarding HPV vaccination is insufficient, indicating the need for educational interventions.

Keywords : HPV Vaccination, Knowledge, Undergraduate Students, Cervical Cancer.

References :

1. Di Giuseppe G, Angelillo S, Bianco A, Gallè F, Licata F, Liguori G, Napolitano F, Nobile CGA, Pavia M, Pelullo CP, Angelillo IF. Evaluating knowledge, attitudes, and behaviors toward HPV infection and vaccination among university students in Italy. Vaccines (Basel). 2023;11(2): doi:10.3390/vaccines1102XXXX.
2. Endarti D, Satibi, Kristina SA, Farida MA, Rahmawanti Y, Andriani T. Knowledge, perception, and acceptance of HPV vaccination and screening for cervical cancer among women in Yogyakarta Province, Indonesia. Asian Pac J Cancer Prev. 2018;19(4):1105–1111. doi:10.22034/APJCP.2018.19.4.1105.
3. Shrestha S, Dhakal P, Bhattarai S, Chauhan R, Shrestha B. Knowledge, attitude and practice regarding HPV vaccination among undergraduate students in Nepal. J Nepal Health Res Counc. 2021;19(2):321–326.
4. Arti, Parwej S. A study to assess knowledge regarding human papilloma virus infection and cervical cancer among college girls in selected colleges of district Patiala, Punjab. International Journal of Nursing and Medical Investigation. 2019;4(3):1–5.
5. He J, He L. Knowledge of HPV and acceptability of HPV vaccine among women in western China: a cross-sectional survey.BMC Womens Health. 2018;18:130. doi:10.1186/s12905-018-0619-8.
6. Sain Y, Reddipogu HT, Kollabathula C, Pinjar MJ. Assessment of knowledge, awareness, and attitude regarding human papillomavirus vaccine among young tribal women in India. Cureus. 2025;17(6):e85746. doi:10.7759/cureus.85746.
7. Chen L, Song Y, Ruan G, Zhang Q, Lin F, Zhang J, et al. Knowledge and attitudes regarding HPV and vaccination among Chinese women aged 20 to 35 years in Fujian Province: a cross-sectional study. Cancer Control.2018;25:1-9.doi:10.1177107327481877 5356
8. Petkar PB, Baghel RS, Mendhe HG. A cross-sectional descriptive study to assess the knowledge, attitudes and practices regarding cancer preventive vaccines among undergraduate medical students. Niger Postgrad Med J.  2025;32(2):147–153. Doi:104103 npmj.npmj_13_25.
9. Das NE, Francis PT. HPV vaccine knowledge and coverage among female students in a medical college, Kerala. International Journal of Community Medicine and Public Health. 2018;5(7):2788–2792.
10. Mekonnen BA, Anagaw YK, Kassahun BA, Worku MC. Evaluation of female university students' knowledge, attitudes, and practices toward human papillomavirus infection and vaccination: multicenter cross-sectional study. BMC Womens Health. 2024;24(1):437. doi:10.1186/s12905-024-03279-6.
11. World Health Organization. Global strategy to accelerate the elimination of cervical cancer as a public health problem. Geneva: WHO; 2020.
12. Chan ZC, Chan TS, Ng KK, Wong ML. A systematic review of literature about women’s knowledge and attitudes toward human papillomavirus (HPV) vaccination. Public Health Nurs. 2012;29(6):481–9.
13. Chan ZC, Chan TS, Ng KK, Wong ML. A systematic review of literature about women’s knowledge and attitudes toward human papillomavirus (HPV) vaccination. Public Health Nurs. 2012 Nov;29(6):481–489. doi:10.1111/j.1525-1446.2012.01022.x.
14. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209-249.
15. Bruni L, Albero G, Serrano B, Mena M, Collado JJ, Gómez D, et al. Human papillomavirus and related diseases in India. HPV Information Centre Report. Barcelona: ICO/IARC; 2018.
16. Bhatla N, Singhal S. Primary HPV screening for cervical cancer. Best Pract Res Clin Obstet Gynaecol. 2020;65:98-108.
17. Singh P, Gupta S, Yadav R. Prevalence of cervical lesions among women attending gynecology outpatient department in a tertiary care hospital. J Obstet Gynecol India. 2017;67(2):123-128.
18. Basu P, Mittal S, Banerjee D, Singh P, Panda CK. Prevalence of high-risk human papillomavirus infection among Indian women: A community-based study. Indian J Cancer. 2016;53(4):534-539.
19. Arbyn M, Weiderpass E, Bruni L, Sanjosé S, Saraiya M, Ferlay J, et al.  Estimates of incidence and mortality of cervical cancer in India: A global analysis. Lancet Glob Health. 2021;9(2):e191-e203.
20. Sankaranarayanan R, Nene BM, Shastri SS, Jayant K, Muwonge R, Budukh AM, et al. HPV screening for cervical cancer in rural India. N Engl J Med. 2009;360(14):1385-1394.
21. Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global burden of cancer: GLOBOCAN estimates of incidence and mortality worldwide. CA Cancer J Clin. 2018;68(6):394-424.
22. National Cancer Registry Programme. Cancer incidence in Kerala: Population-based cancer registry report. Bengaluru: Indian Council of Medical Research; 2018.
23. Nair MK, Varghese C, Swaminathan R. Prevalence of cervical abnormalities among women attending screening clinics in Kerala. Indian J Med Res. 2016;144(3):343-349.
24. Shetty V, Shetty AK, Shetty J. Prevalence of human papillomavirus infection among women attending cervical screening clinics in Karnataka. J Clin Diagn Res. 2017;11(5):DC05-DC08.2
25. World Health Organization. Global strategy to accelerate the elimination of cervical cancer as a public health problem. Geneva: WHO; 2022.cine among adult females in urban India: a cross-sectional study. Int J Acad Med Pharm. 2025;7(3):90-94. (Study showed only 10.5% had heard of HPV vaccine).
26. Hoque ME, Ghuman S, Coetzee C. Knowledge of human papillomavirus and self-sampling including vaccination practices among female students in the Free State, South Africa. Afr J Reprod Health. 2014;18(4):138–146
27. Singh A, Gupta S, Kumar R. Awareness of cervical cancer and HPV vaccine among women in Delhi and Rohtak, India: a comparative cross-sectional study. Asian Pac J Cancer Prev. 2012;13(11):5445–5449
28. Pandey D, Vanya V, et al Awareness and acceptability of human papillomavirus vaccine among medical students in a tertiary care hospital in India. J Obstet Gynaecol India. 2012;62(5):531–535.
29. Thakkar N, Aswathy S, Agarwal S. Knowledge, attitude and awareness of HPV vaccination among medical students in Gujarat, India. J Clin Diagn Res. 2014;8(6):XC01–XC04.
30. Saha A, Chaudhury AN, et al Awareness of cervical cancer and HPV vaccine among medical, dental and nursing students in South India. Asian Pac J Cancer Prev. 2010;11(2):473–476.
31. Di Giuseppe G, Abbate R ,et al Human papillomavirus and vaccination: knowledge, attitudes and behaviour among medical students. Vaccine. 2008;26(15):1900–1903.
32. Patel H, Jeve YB, Sherman SM, Moss EL. Knowledge of human papillomavirus and the HPV vaccine in Central India: a cross-sectional study. J Obstet Gynaecol. 2016;36(4):505
33. Mehta S, Rajaram S, Goel G, Goel N. Awareness about human papillomavirus and its vaccine among medical students. Indian J Community Med. 2020;45(2):175–179.
34. Saha A, Chaudhury AN, Bhowmik P, Chatterjee R. Awareness of cervical cancer among female students of premier colleges in Kolkata, India. Asian Pac J Cancer Prev. 2010;11(4):1085–1090.
35. Wong LP, Sam IC. Ethnically diverse female university students’ knowledge and attitudes toward human papillomavirus (HPV), HPV vaccination and cervical cancer. Eur J Obstet Gynecol Reprod Biol. 2010;148(1):90–95.
36. Makwe CC, Anorlu RI. Knowledge of and attitude toward human papillomavirus infection and vaccines among female nurses at a tertiary hospital in Nigeria. Int J Womens Health. 2011;3:313–317.
37. Yilmazel G, Duman NB. Knowledge, attitudes and beliefs about cervical cancer and HPV vaccination among college students in Turkey. Asian Pac J Cancer Prev. 2014;15(18):7699–7704.
38. Aswathy S, Quereshi MA, Kurian B, Leelamoni K. Cervical cancer screening: Current knowledge & practice among women in a rural population of Kerala, India. Indian J Med Res. 2012;136(2):205–210.
39. George CE, Basu P, Taneja N, et al. A study on knowledge and awareness of HPV vaccination among college students in South India. J Family Med Prim Care. 2021;10(1):220–225.
40. Lee PW, Kwan TT, et al Beliefs about cervical cancer and HPV vaccination among Chinese women in Hong Kong. BMC Public Health. 2010;10:486.
41. Kwan TT, Chan KK, et al Acceptability of human papillomavirus vaccination among Chinese women: concerns and implications. BJOG. 2009;116(4):501–510.
42. Remschmidt C, Walter D, et al Knowledge, attitude, and uptake related to HPV vaccination among young women in Germany. Vaccine. 2014;32(29):3500–3505
43. Rakheja S, Mehta D,et al Knowledge, attitude and awareness of HPV vaccination among college-going girls (18–26 years) in Delhi NCR. Asian Pac J Cancer Care.2025;10(1):1–8.
44. Sewidan A, ElSherbiny AM, et al Assessment of awareness, knowledge, and attitude of Suez University medical students towards human papilloma virus vaccine (HPV): a cross-sectional study. Egypt J Fertil Steril. 2024;28(1):21–27.
45. Sozib SI, Smail L, et al Knowledge, attitudes, and practices regarding HPV infection, cervical cancer, and HPV vaccination among Emirati women. Future Oncol.2025;21(27):3 561–3571.
46. Anto PV, Balaji VK,et al Knowledge, attitudes, and practices (KAP) regarding HPV infection and vaccination among women aged ≥30 years: a cross-sectional study. Int J Environ Sci. 2025;11(15s):2196-2200.
47. Furqan S, Mondal A, et al Knowledge and awareness of Human Papillomavirus vaccination in an urbanized village in Delhi. Cureus. 2025;17(5):e84512.
48. Azzi A, Al-Dhelaan R,et al. Assessment of awareness level among women about cervical smears, human papillomavirus (HPV), and HPV vaccine in Saudi Arabia. Scientific Reports. 2025;15:44171.
49. Furqan S, Mondal A, et al Knowledge and awareness of human papillomavirus vaccination in an urbanized village in Delhi. Cureus. 2025;17(5):84512.
50. Azzi A, Al-Dhelaan R, et al Assessment of awareness level among women about cervical smears, human papillomavirus (HPV), and HPV vaccine in Saudi Arabia. Sci Rep. 2025;15:44171.
51. Datta M, Roy S, et al Knowledge, attitudes and HPV vaccine intention among women in India. J Community Health. 2022;47(4):593–601.