AIDS is caused by the Human Immunodeficiency Virus, which originated in non-human primates in sub-Saharan Africa and was transferred to humans during the late 19th or early 20th century. Since the time first case was detected in USA in 1981, the HIV/AIDS epidemic continues its expansion across the globe. The first AIDS case in India was reported in may1986. In India the HIV/AIDS epidemic is now more than one and a half-decade old. Within this period it has emerged as one of the most serious public health problems in the country. More devastating condition is the mental status of those people. Their quality of life is more hammered because of the social isolation and poor stigma. Many measures have been adopted by governmental and nongovernmental agencies to improve the quality of life of PLWHIV, but the distribution is so wide that the coverage of such help is falling short.

Keywords : Acquired Immune Deficiency Syndrome, Human Immune deficiency virus, People Living with HIV/AIDS Quality of life, World Health Organization, Analysis of variance, Health Related Quality Of Life, Sexually Transmitted Diseases, National AIDS Control Organiz