Oxoindolines are interesting heterocyclic compounds which show diverse biological significance. In this oxoindolines was prepared by one-pot condensation reaction of isatin, dimedone, and various active methylene using piperidine as a basic catalyst and solvent as methanol, under stirring at ambient temperature. The final products were characterized by FT-IR spectroscopy, Massspectroscopy, 1H NMR-spectroscopy and 13C NMRspectroscopy.

Keywords : MCRS, Isatin, Dimedone, Oxoindolines, Antimicrobial Estimation.