Background: Many years have passed since the severe acute respiratory syndrome coronavirus 2 pandemic started, no specific treatment against the disease is available. Pregnant women are at increased risk of severe disease, intensive care unit admission, and invasive ventilation when compared with non-pregnant patients of the same age. Therefore, pregnant women are classified as a high-risk population for COVID-19 infection. Methodology: This Cross-sectional study was conducted at Department of Obstetrics & Gynecology, PIMS MCH, Islamabad for a period of three months. Structured questionnaire was given to partcipants which focused on demographics, medical comorbidities, perception of COVID-19 infection and risk of infection, barriers to vaccination, preferred source of medical information, vaccine acceptance, vaccine uptake, and reasons for unwillingness to receive the COVID-19 vaccine decision. Results: The study included a total of 200 pregnant women.The mean age of the participants was 25 years, ranging from minimum age of 19 years to maximum age of 37 years.Conclusion: COVID-19 vaccination during pregnancy presents an opportunity to protect both maternal and fetal health, based on available evidence and current understanding. While data on vaccine safety during pregnancy is growing, it is important to acknowledge that research is ongoing, and recommendations may evolve as new information emerges.

Keywords : COVID-19, Vaccination, Pregnancy, Acceptance.