Acute Respiratory Distress Syndrome among Premature Neonates: Prevalence, Mortality rate and Risk Factors of Mortality


Authors : Al-Aghbari, Nasher; Al-Sonboli, Najla; Al-Azazi, Ebraheem

Volume/Issue : Volume 8 - 2023, Issue 4 - April

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://tinyurl.com/4d2jdn93

DOI : https://doi.org/10.5281/zenodo.8281001

Abstract : Introduction: Prematurity is one of the major challenges in neonatology worldwide. Death due to Acute respiratory distress syndrome (ARDS) represents the main cause of death among premature babies. Aim: To identify the risk factors of death due to ARDS among premature neonates. Methodology: A retrospective hospital based study was conducted over one year from October 2021 to October 2022 at Al-Sabeen Hospital for Maternity and childhood in Sana'a, Yemen. A pre-designed questionnaire using Google form was used to fill out the data of the patients' retrieved from their hospital's records. Epi-Info program No. 7 was used to analyse the data. Results: Out of 1086 admitted neonates, 577 premature babies were found eligible to be enrolled in the study. One hundred and nineteen (20.6%) were died. Gestational age < 30 weeks, weight <1.5 kg, Apgar score <7, male sex, being on mechanical ventilator and lack antenatal care were found to be independent significant risk factors on multivariate logistic regression analysis for death among premature neonates with RDS. Conclusion: The risk factors associated to deaths among premature neonates with RDS highlight the exceptional characteristics of the health care that should be provided to mothers and infants in areas such as Sana’a, Yemen, where concerns related to quality of care need distinctive attention.

Keywords : Neonate, Preterm, Acute Respiratory Distress syndrome, Prevalence, Risk factor, Sana'a.

Introduction: Prematurity is one of the major challenges in neonatology worldwide. Death due to Acute respiratory distress syndrome (ARDS) represents the main cause of death among premature babies. Aim: To identify the risk factors of death due to ARDS among premature neonates. Methodology: A retrospective hospital based study was conducted over one year from October 2021 to October 2022 at Al-Sabeen Hospital for Maternity and childhood in Sana'a, Yemen. A pre-designed questionnaire using Google form was used to fill out the data of the patients' retrieved from their hospital's records. Epi-Info program No. 7 was used to analyse the data. Results: Out of 1086 admitted neonates, 577 premature babies were found eligible to be enrolled in the study. One hundred and nineteen (20.6%) were died. Gestational age < 30 weeks, weight <1.5 kg, Apgar score <7, male sex, being on mechanical ventilator and lack antenatal care were found to be independent significant risk factors on multivariate logistic regression analysis for death among premature neonates with RDS. Conclusion: The risk factors associated to deaths among premature neonates with RDS highlight the exceptional characteristics of the health care that should be provided to mothers and infants in areas such as Sana’a, Yemen, where concerns related to quality of care need distinctive attention.

Keywords : Neonate, Preterm, Acute Respiratory Distress syndrome, Prevalence, Risk factor, Sana'a.

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