Authors :
Nitu Saha; Rituparna Mondal; Arunima Banerjee; Rupa Debnath; Siddhartha Chatterjee
Volume/Issue :
Volume 10 - 2025, Issue 6 - June
Google Scholar :
https://tinyurl.com/35nznu6y
DOI :
https://doi.org/10.38124/ijisrt/25jun1801
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Note : Google Scholar may take 30 to 40 days to display the article.
Abstract :
Lung cancer is a leading cause of cancer-related death globally, necessitating innovative diagnostic methods to
enhance early detection and improve treatment effectiveness. This study presents "Advanced DeepLungCareNet," an
enhanced deep learning framework designed to predict and classify lung cancer from medical imaging data with greater
accuracy and reliability. The approach improves diagnostic efficacy by employing convolutional neural networks (CNNs)
and incorporating sophisticated image processing algorithms. The study utilized the IQ-OTH/NCCD Lung Cancer Dataset
from Kaggle, which includes a diverse collection of annotated medical images, such as computed tomography (CT) scans
and X-rays. Data preprocessing included normalization, augmentation, and segmentation to improve input quality for the
neural network. The model architecture has been refined with deeper convolutional layers, optimized pooling techniques,
and sophisticated feature extraction algorithms, enabling the detection of minute anomalies and patterns in the imaging
data. The performance evaluation metrics, including accuracy, precision, recall, F1-score, and AUC-ROC, illustrate the
superiority of "Advanced DeepLungCareNet" over existing state-of-the-art models. The framework achieved exceptional
sensitivity and specificity, reducing false positives and false negatives, which is crucial for clinical reliability. The model
demonstrated remarkable accuracy in detecting lung cancer from CT scans, making it a valuable tool for assisting healthcare
professionals in early diagnosis. This study emphasizes the transformative potential of "Advanced DeepLungCareNet" in
clinical environments, offering a robust solution for the early diagnosis and risk evaluation of lung cancer. Future attempts
will focus on integrating multi-modal datasets, incorporating real-world clinical data, and exploring transfer learning
approaches to enhance and validate the model's effectiveness across various healthcare situations.
Keywords :
Advanced Deeplungcarenet, Lung Cancer, Machine Learning, Medical Imaging, Deep Learning, Convolutional Neural Networks (CNN), Resnet50, Computed Tomography (CT) Scans, Early Cancer Detection, Grad-CAM, Diagnostic Accuracy, Privacy in AI, IQ-OTH/NCCD Lung Cancer Dataset, Adam Optimizer.
References :
- Z. Obermeyer and E. J. Emanuel, “Predicting the Future — Big Data, Machine Learning, and Clinical Medicine,” New England Journal of Medicine, vol. 375, no. 13, pp. 1216–1219, Sep. 2016.
- Li et al., “Global burden and trends of lung cancer incidence and mortality,” Chin Med J (Engl), vol. 136, no. 13, p. 1583, Jul. 2023.
- American Cancer Society, “Lung Cancer Statistics | How Common is Lung Cancer?” Accessed: Jun. 18, 2025.
- W. L. Bi et al., “Artificial intelligence in cancer imaging: Clinical challenges and applications,” CA Cancer J Clin, vol. 69, no. 2, pp. 127–157, Mar. 2019.
- Ardila et al., “End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography,” Nat Med, vol. 25, no. 6, pp. 954–961, Jun. 2019.
- Esteva et al., “Dermatologist-level classification of skin cancer with deep neural networks,” Nature 2017 542:7639, vol. 542, no. 7639, pp. 115–118, Jan. 2017.
- M. Cellina et al., “Artificial Intelligence in Lung Cancer Screening: The Future Is Now,” Cancers (Basel), vol. 15, no. 17, Sep. 2023.
- H. Conor, “Google’s cancer-spotting AI outperforms radiologists in reading lung CT scans | Fierce Biotech.” Accessed: Jun. 18, 2025.
- Hosny, C. Parmar, J. Quackenbush, L. H. Schwartz, and H. J. W. L. Aerts, “Artificial intelligence in radiology,” Nat Rev Cancer, vol. 18, no. 8, pp. 500–510, Aug. 2018.
- R. Debnath, R. Mondal, A. Chakraborty, and S. Chatterjee, “Advances in Artificial Intelligence for Lung Cancer Detection and Diagnostic Accuracy: A Comprehensive Review,” Int J Innov Sci Res Technol, pp. 1579–1586, May 2025.
- Das, R. Debnath, and D. Khatua, “Online Framework of Examination for Evaluating Learner’s Knowledge,” International Journal of Education and Management Engineering, vol. 14, no. 6, p. 58, Dec. 2024.
- H. Arimura et al., “Computerized scheme for automated detection of lung nodules in low-dose computed tomography images for lung cancer screening,” Acad Radiol, vol. 11, no. 6, pp. 617–629, 2004.
- A. A. Setio et al., “Validation, comparison, and combination of algorithms for automatic detection of pulmonary nodules in computed tomography images: The LUNA16 challenge,” Med Image Anal, vol. 42, pp. 1–13, Dec. 2017.
- K. H. Yu, A. L. Beam, and I. S. Kohane, “Artificial intelligence in healthcare,” Nature Biomedical Engineering 2018 2:10, vol. 2, no. 10, pp. 719–731, Oct. 2018.
- Hosny, C. Parmar, J. Quackenbush, L. H. Schwartz, and H. J. W. L. Aerts, “Artificial intelligence in radiology,” Nature Reviews Cancer 2018 18:8, vol. 18, no. 8, pp. 500–510, May 2018.
- Y. LeCun, L. Bottou, Y. Bengio, and P. Haffner, “Gradient-based learning applied to document recognition,” Proceedings of the IEEE, vol. 86, no. 11, pp. 2278–2323, 1998.
- Q. Li, W. Cai, X. Wang, Y. Zhou, D. D. Feng, and M. Chen, “Medical image classification with convolutional neural network,” 2014 13th International Conference on Control Automation Robotics and Vision, ICARCV 2014.
- Krizhevsky, I. Sutskever, and G. E. Hinton, “ImageNet classification with deep convolutional neural networks,” Commun ACM, vol. 60, no. 6, pp. 84–90, Jun. 2017.
- S. M. Lundberg, P. G. Allen, and S.-I. Lee, “A Unified Approach to Interpreting Model Predictions”, 2017.
- D. Sarwate and K. Chaudhuri, “Signal processing and machine learning with differential privacy: Algorithms and challenges for continuous data,” IEEE Signal Process Mag, vol. 30, no. 5, pp. 86–94, 2013.
- T. Li, A. K. Sahu, A. Talwalkar, and V. Smith, “Federated Learning: Challenges, Methods, and Future Directions,” IEEE Signal Process Mag, vol. 37, no. 3, pp. 50–60, May 2020.
- R. Debnath, G. Senthil, “Semi-Trusted Third Party Using Dynamic Grid System for Location-Based Services, Networking, and Communication.” Accessed: Jun. 07, 2025.
- M. Komorowski and L. A. Celi, “Will artificial intelligence contribute to overuse in healthcare?,” Crit Care Med, vol. 45, no. 5, pp. 912–913, May 2017.
- Ghosh, P., Hazra, S., & Chatterjee, S, “Future Prospects Analysis in Healthcare Management Using Machine Learning Algorithms.” Accessed: Jun. 19, 2025.
- M. Ghassemi, L. Oakden-Rayner, and A. L. Beam, “The false hope of current approaches to explainable artificial intelligence in health care,” Lancet Digit Health, vol. 3, no. 11, pp. e745–e750, Nov. 2021.
- R. L. Siegel, K. D. Miller, and A. Jemal, “Cancer statistics, 2020,” CA Cancer J Clin, vol. 70, no. 1, pp. 7–30, Jan. 2020.
- Hazra, S., Mahapatra, S., Chatterjee, S., & Pal, D., “Automated Risk Prediction of Liver Disorders Using Machine Learning.” Accessed: May 18, 2025.
- Gon, S. Hazra, S. Chatterjee, and A. K. Ghosh, “Application of Machine Learning Algorithms for Automatic Detection of Risk in Heart Disease,” Cognitive Cardiac Rehabilitation Using IoT and AI Tools, pp. 166–188, Jan. 2023.
- J. Topol, “High-performance medicine: the convergence of human and artificial intelligence”, 2019.
- H. J. W. L. Aerts et al., “Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach,” Nat Commun, vol. 5, no. 1, pp. 1–9, Jun. 2014.
- Esteva et al., “A guide to deep learning in healthcare,” Nat Med, vol. 25, no. 1, pp. 24–29, Jan. 2019.
- S. Das, S. Chatterjee, S. Bhattacharya, S. Mitra, A. Adhikary, and N. C. Giri, “Movie ’s-Emotracker: Movie Induced Emotion Detection by Using EEG and AI Tools,” Lecture Notes in Electrical Engineering, vol. 1046 LNEE, pp. 583–595, 2023.
- R. Chatterjee, S. Chatterjee, S. Samanta, and S. Biswas, “AI Approaches to Investigate EEG Signal Classification for Cognitive Performance Assessment,” Proceedings - International Conference on Computational Intelligence and Networks, 2024.
- S. Das, S. Chatterjee, A. I. Karani, and A. K. Ghosh, “Stress Detection While Doing Exam Using EEG with Machine Learning Techniques,” pp. 177–187, 2024.
- S. Das, S. Chatterjee, D. Sarkar, and S. Dutta, “Comparison Based Analysis and Prediction for Earlier Detection of Breast Cancer Using Different Supervised ML Approach,” pp. 255–267, 2023.
- K. He, X. Zhang, S. Ren, and J. Sun, “Deep Residual Learning for Image Recognition,” Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition, vol. 2016-December, pp. 770–778, Dec. 2015.
- S. Hazra et al., “Pervasive Nature of AI in the Health Care Industry: High-Performance Medicine,” International Journal of Research and Analysis in Science and Engineering, vol. 4, no. 1, pp. 16–16, Jan. 2024.
- Adhikary, S. Das, R. Mondal, and S. Chatterjee, “Identification of Parkinson’s Disease Based on Machine Learning Classifiers,” pp. 490–503, 2024.
- P. Ghosh, R. Dutta, N. Agarwal, S. Chatterjee, and S. Mitra, “Social Media Sentiment Analysis on Third Booster Dosage for COVID-19 Vaccination: A Holistic Machine Learning Approach,” Lecture Notes in Electrical Engineering, vol. 985, pp. 179–190, 2023.
Lung cancer is a leading cause of cancer-related death globally, necessitating innovative diagnostic methods to
enhance early detection and improve treatment effectiveness. This study presents "Advanced DeepLungCareNet," an
enhanced deep learning framework designed to predict and classify lung cancer from medical imaging data with greater
accuracy and reliability. The approach improves diagnostic efficacy by employing convolutional neural networks (CNNs)
and incorporating sophisticated image processing algorithms. The study utilized the IQ-OTH/NCCD Lung Cancer Dataset
from Kaggle, which includes a diverse collection of annotated medical images, such as computed tomography (CT) scans
and X-rays. Data preprocessing included normalization, augmentation, and segmentation to improve input quality for the
neural network. The model architecture has been refined with deeper convolutional layers, optimized pooling techniques,
and sophisticated feature extraction algorithms, enabling the detection of minute anomalies and patterns in the imaging
data. The performance evaluation metrics, including accuracy, precision, recall, F1-score, and AUC-ROC, illustrate the
superiority of "Advanced DeepLungCareNet" over existing state-of-the-art models. The framework achieved exceptional
sensitivity and specificity, reducing false positives and false negatives, which is crucial for clinical reliability. The model
demonstrated remarkable accuracy in detecting lung cancer from CT scans, making it a valuable tool for assisting healthcare
professionals in early diagnosis. This study emphasizes the transformative potential of "Advanced DeepLungCareNet" in
clinical environments, offering a robust solution for the early diagnosis and risk evaluation of lung cancer. Future attempts
will focus on integrating multi-modal datasets, incorporating real-world clinical data, and exploring transfer learning
approaches to enhance and validate the model's effectiveness across various healthcare situations.
Keywords :
Advanced Deeplungcarenet, Lung Cancer, Machine Learning, Medical Imaging, Deep Learning, Convolutional Neural Networks (CNN), Resnet50, Computed Tomography (CT) Scans, Early Cancer Detection, Grad-CAM, Diagnostic Accuracy, Privacy in AI, IQ-OTH/NCCD Lung Cancer Dataset, Adam Optimizer.