An Excellent Response to Chemotherapy in a Young Patient Diagnosed with Undifferentiated Pleomorphic Sarcoma: A Case Report and Review of Literature


Authors : Dr. Harsh Aggarwal; Dr. Vibhor Garg; Dr. Sonika Lamba; Dr. Shubham Gupta; Dr. Aneeshya CK

Volume/Issue : Volume 8 - 2023, Issue 4 - April

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://bit.ly/415psH5

DOI : https://doi.org/10.5281/zenodo.7894400

Abstract : Undifferentiated pleomorphic sarcoma (UPS) was earlier termed as malignant fibrous histiocytoma (MFH). UPH mainly affects extremities and retroperitoneum with the age predisposition of 50+. We present a case of 16 year old boy with malignant UPS; primary in thigh with lung metastases showing an excellent response to multidisciplinary approach involving surgeryfollowed by systemic combination chemotherapy. The treatment of the patient with metastatic UPS/MFH was successfulutilizing a multidisciplinary approach; although, this type of sarcoma carries a poor prognosis and seen to be insensitive to both chemotherapy and radiotherapy.

Keywords : Undifferentiated pleomorphic sarcoma, Malignant fibrous histiocytoma, Chemo radiotherapy.

Undifferentiated pleomorphic sarcoma (UPS) was earlier termed as malignant fibrous histiocytoma (MFH). UPH mainly affects extremities and retroperitoneum with the age predisposition of 50+. We present a case of 16 year old boy with malignant UPS; primary in thigh with lung metastases showing an excellent response to multidisciplinary approach involving surgeryfollowed by systemic combination chemotherapy. The treatment of the patient with metastatic UPS/MFH was successfulutilizing a multidisciplinary approach; although, this type of sarcoma carries a poor prognosis and seen to be insensitive to both chemotherapy and radiotherapy.

Keywords : Undifferentiated pleomorphic sarcoma, Malignant fibrous histiocytoma, Chemo radiotherapy.

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