An Integrated Review of Hepatorenal Syndrome


Authors : Alwala Nitisha; Jangam Pratyusha; Samala Shika

Volume/Issue : Volume 9 - 2024, Issue 7 - July


Google Scholar : https://shorturl.at/VvnLR

Scribd : https://shorturl.at/T4CWW

DOI : https://doi.org/10.38124/ijisrt/IJISRT24JUL1485

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : The purpose of this review was to go over and condense the intricate details that have been updated over time about the diagnosis, etiopathology, definition, and available treatments for hepatorenal syndrome. When individuals have decompensated liver disease, acute kidney injury might have multiple causes, including hormone replacement therapy (HRS). Type 1 and type 2 are the two clinical subtypes of hepatorenal syndrome. Lack of proteinuria, hematuria, or aberrant renal ultrasonography, as well as declining kidney function, are the basis for the diagnosis. Liver transplantation is the best treatment for cases of HRS, but because of the high death rate, very few people get one. In light of the improved understanding of the condition, more hepatorenal syndrome therapeutic options, including pharmacological and non-pharmacological techniques, are also explored.

Keywords : Liver Transplant, Cirrhosis, Terlipressin, Kidney Failure, Diagnostic, Treatment, and Hepatorenal Syndrome.

References :

  1. Alicia S. Ojeda-Yuren, Eira Cerda-Reyes, Maria R. Herrero-Maceda, Graciela Castro-Narro, Salvatore Piano, An Integrated Review of the Hepatorenal Syndrome, Volume 22, May–June 2021, 100236.
  2. Indika R. Ranasinghe, Bashar Sharma, Khalid Bashir, Hepatorenal Syndrome, August 8, 2023.
  3. Thomas A. Gonwa, MD, Professor of Medicine, Mayo Clinic College of Medicine, Chairman, Department of Transplantation, Mayo Clinic, Florida, for assistance in the preparation of this report, Hepatorenal Syndrome, 09/30/2022.
  4. G. Low, G. J. M. Alexander, D. J. Lomas  , Hepatorenal Syndrome: Aetiology, Diagnosis, and Treatment , 2015 Jan 12.
  5. Steven L. Flamm, Kimberly Brown,  Hani M. Wadei, Robert S. Brown, Jr., Marcelo Kugelmas, Milagros Samaniego‐Picota,  Patrizia Burra,  Fred Poordad,  and Sammy Saab, The Current Management of Hepatorenal Syndrome–Acute Kidney Injury in the United States and the Potential of Terlipressin, 2021 Jul 14.

The purpose of this review was to go over and condense the intricate details that have been updated over time about the diagnosis, etiopathology, definition, and available treatments for hepatorenal syndrome. When individuals have decompensated liver disease, acute kidney injury might have multiple causes, including hormone replacement therapy (HRS). Type 1 and type 2 are the two clinical subtypes of hepatorenal syndrome. Lack of proteinuria, hematuria, or aberrant renal ultrasonography, as well as declining kidney function, are the basis for the diagnosis. Liver transplantation is the best treatment for cases of HRS, but because of the high death rate, very few people get one. In light of the improved understanding of the condition, more hepatorenal syndrome therapeutic options, including pharmacological and non-pharmacological techniques, are also explored.

Keywords : Liver Transplant, Cirrhosis, Terlipressin, Kidney Failure, Diagnostic, Treatment, and Hepatorenal Syndrome.

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