Analysis of Radiographic Patterns and Associated Co-Morbidities in Newly Diagnosed Sputum-Positive Pulmonary Tuberculosis in Adult Population of Either Gender in a Tertiary Care Centre Hapur Uttar Pradesh


Authors : Dr. Raman Pasrija; Dr Ashish Kaushik; Dr. Shubhendu Gupta; Dr Lalit Garg

Volume/Issue : Volume 9 - 2024, Issue 7 - July


Google Scholar : https://shorturl.at/hzfSL

Scribd : https://shorturl.at/6zKBi

DOI : https://doi.org/10.38124/ijisrt/IJISRT24JUL1634

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Background Pulmonary tuberculosis often results in notable chest radiographic abnormalities. Older adults and individuals with existing co-morbid conditions are especially susceptible to developing more severe forms of TB. This study explores the impact of age and co- morbidities on the radiographic presentation of pulmonary tuberculosis.  Objective To evaluate the chest radiographic features and associated co-morbidities in adults over 18 years of age who have recently been diagnosed with sputum-positive pulmonary tuberculosis.  Materials & Method: An observational study was carried out involving 70 adults newly diagnosed with sputum-positive pulmonary tuberculosis. The study documented both chest radiographic abnormalities and associated co- morbidities.  Results: The study comprised 70 individuals who had recently received a diagnosis of sputum-positive pulmonary tuberculosis. The mean age of study population was 49.64 years and majority of patients were male (61.4%) and rest (38.6%) were female. Of the radiological lesion seen on chest x-rays, the most prevalent ones were patchy infiltrates (82.9%). Radiological findings of infiltration and cavitation were found to be the most in recently diagnosed sputum- positive pulmonary tuberculosis. Most common comorbidity associated with pulmonary tuberculosis was Diabetes Mellitus. Bilateral lesion on chest radiology in sputum positive PTB was commonly seen in patients with Diabetes Mellitus.  Conclusion: Our investigation revealed that newly diagnosed sputum positive PTB patients often exhibited chest X-ray abnormalities such as infiltration, cavitary lesions, and comorbidities such diabetes and anemia. This study also demonstrates that elderly patients with pulmonary tuberculosis had a greater incidence of comorbidities and unusual radiological findings. Therefore, it is completely justified to maintain a high level of suspicion for tuberculosis in the aged population.

Keywords : Radiographic Abnormalities; Diabetes Mellitus; Bacterial Load; Mycobacterium Tuberculosis.

References :

  1. Cambau E, Drancourt M. Steps towards the discovery of Mycobacterium tuberculosis by Robert Koch, 1882. Clin Microbiol Infect. 2014;20:196-201.
  2. World Health Organization. Global tuberculosis report 2018. Available at: http://www.who.int/news-room/fact-sheets/detail/tuberculosis. Accessed in 18 September 2018.
  3. Rehm J, Andriy V Samokhvalov, Manuela G Neuman, Robin Room, Charles Parry, Knut Lonnroth et al. The association between alcohol use, alcohol use disorders and tuberculosis (TB): A systematic review. BMC Public Health. 2009;9:450-56.
  4. Zaheer akhtar, Usman javed iqbal, Hamid hassan. Chest X-ray findings in sputum positive tuberculosis patients. J Fatima Jinnah Med Coll Lahore. 2014;8:21-3.
  5. Sefa Levent Ozsahin, Sulhattin Arslan, KursatEpozturk. Chest X-ray and bacteriology in the initial phase of treatment of 800 male patients with pulmonary tuberculosis. J Bras Pneumol. 2011;37(3):294-301.
  6. Arun Babu.V, Subramanian.S, Meenakshi.N, Ragulan R, Vishwambar v, Apar J. Comparison of clinico-radiological profile of new smear positive pulmonary tuberculosis cases among adults and elderly people. Int J Sci Res. 2015;4:1003-5.
  7. W-J. Su, J-Y. Feng, Y-C. Role of 2-month sputum smears in predicting culture conversion in pulmonary tuberculosis. Eur Respir J. 2011;37:376-83.

Background Pulmonary tuberculosis often results in notable chest radiographic abnormalities. Older adults and individuals with existing co-morbid conditions are especially susceptible to developing more severe forms of TB. This study explores the impact of age and co- morbidities on the radiographic presentation of pulmonary tuberculosis.  Objective To evaluate the chest radiographic features and associated co-morbidities in adults over 18 years of age who have recently been diagnosed with sputum-positive pulmonary tuberculosis.  Materials & Method: An observational study was carried out involving 70 adults newly diagnosed with sputum-positive pulmonary tuberculosis. The study documented both chest radiographic abnormalities and associated co- morbidities.  Results: The study comprised 70 individuals who had recently received a diagnosis of sputum-positive pulmonary tuberculosis. The mean age of study population was 49.64 years and majority of patients were male (61.4%) and rest (38.6%) were female. Of the radiological lesion seen on chest x-rays, the most prevalent ones were patchy infiltrates (82.9%). Radiological findings of infiltration and cavitation were found to be the most in recently diagnosed sputum- positive pulmonary tuberculosis. Most common comorbidity associated with pulmonary tuberculosis was Diabetes Mellitus. Bilateral lesion on chest radiology in sputum positive PTB was commonly seen in patients with Diabetes Mellitus.  Conclusion: Our investigation revealed that newly diagnosed sputum positive PTB patients often exhibited chest X-ray abnormalities such as infiltration, cavitary lesions, and comorbidities such diabetes and anemia. This study also demonstrates that elderly patients with pulmonary tuberculosis had a greater incidence of comorbidities and unusual radiological findings. Therefore, it is completely justified to maintain a high level of suspicion for tuberculosis in the aged population.

Keywords : Radiographic Abnormalities; Diabetes Mellitus; Bacterial Load; Mycobacterium Tuberculosis.

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