Authors : Widyawati; Andries Pascawinata; Fauzia Nilam Orienty; Wulan Angestisia; Ayyi Rezky Agustine

Volume/Issue : Volume 10 - 2025, Issue 12 - December

Google Scholar : https://tinyurl.com/bddfdvkh

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DOI : https://doi.org/10.38124/ijisrt/25dec815

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Abstract : Background: Dental caries is a form of bacterial infection of the hard tissues of teeth caused by the activity of Streptococcus mutans bacteria in dental plaque. Caries treatment must be comprehensive, encompassing preventive, curative, rehabilitative, and promotive efforts. The use of chemical antibacterials such as chlorhexidine has side effects, so alternatives from natural ingredients are needed. The use of natural ingredients as antibacterials can inhibit bacterial growth, one of which is the gletang plant (Tridax procumbens L.). The purpose of this study was to determine the antibacterial activity of the methanol fraction of the gletang plant (Tridax procumbens L.) with concentrations of 2%, 4%, 6% and 8% against Streptococcus mutans bacteria. This type of research was conducted in vitro with a post-test only control group design. Testing the antibacterial activity of the methanol fraction of the gletang plant (Tridax procumbens L.) used concentrations of 2%, 4%, 6% and 8, chlorhexidine as k (+) and methanol as k (-). The results showed that the methanol fraction of the gletang plant (Tridax procumbens L.) produced an inhibition zone with the average diameter of the inhibition zone increasing with increasing concentration. The highest concentration (8%) produced an inhibition zone of 4.1 mm, while 0.2% chlorhexidine produced an inhibition zone of 5.1 mm. Statistical analysis using the Kruskal-Wallis test showed that there was a significant difference between concentrations on the inhibition zone (p <0.05), this means that the methanol fraction of the gletang plant (Tridax procumbens L.) with concentrations of 2%, 4%, 6% and 8% has the potential as an antibacterial against Streptococcus mutans . The conclusion in this study is that there is antibacterial activity of the methanol fraction of the gletang plant (Tridac procumbens L.) against the growth of Streptococcus mutans bacteria.

Keywords : Streptococcus mutans, Gletang plant, Tridax procumbens L., Inhibition Zone.

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