Authors : KEITA M.; KOLIE B.; BALDE R; CONDE Y

Volume/Issue : Volume 9 - 2024, Issue 11 - November

Google Scholar : https://tinyurl.com/muumdnve

Scribd : https://tinyurl.com/mry69d9b

DOI : https://doi.org/10.38124/ijisrt/IJISRT24NOV633

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Abstract : Antibiotic resistance in bacteria involved in diarrheal diseases is a major public health concern worldwide. To determine the sensitivity profile of Escherichia coli to antibiotics commonly used in the treatment of diarrhea in children aged 1 month to 5 years admitted to Kindia Regional Hospital. This is a prospective cross-sectional and descriptive study that lasted 6 months, from 05 May 2021 to 18 October 2021. A total of 154 diarrheal stool samples were taken, and 50 strains of Escherichia coli were isolated (32.47%). E. coli was most found in the 2–3-year age group (50%), while the 1 month to 1 year age group was least affected (20%). In this study, 54% of Escherichia parcels were recorded in females and 46% in males. It found that E. coli strains were 100% sensitive to Ceftriaxone, Ciprofloxacin and Gentamicin. When Amoxiclav, Cefotaxime, Ceftazidime, Trimethoprim and Nalidixic acid are used, the sensitivity effects on E. coli strains are high, with rates of 90%, 78%, 74%, 70% and 86% respectively. Resistance was low in E. coli strains to Amoxiclav, Cefotaxime, Ceftazidime, Trimethoprim and nalidixic acid, with rates of 10%, 22%, 26%, 30% and 14% respectively. This study recommends that the health authorities set up a national and regional programmed for effective monitoring of antimicrobial use and integrate it into the objectives for improving the quality of care in all health establishments.

Keywords : Diarrhea, Escherichia Coli, Sensitivity, Resistance, Antibiotics, Kindia.

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