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Antibiotic Susceptibility Profile of Diabetic Foot Infection Pathogens in Enugu, Nigeria


Authors : Nonye T. Ujam; Princeton Shekinah; Cyril C. Adonu; Amaka H. Okorie; Restus Onwusaba; Chidimma R. Chukunwejim; Emmanuel Ogudu; Chizoba A. Ozochi; Cornelius Ozochikelu; Christian C. Aneke; Luke J. Ugwu

Volume/Issue : Volume 11 - 2026, Issue 6 - June


Google Scholar : https://tinyurl.com/z62ccmyh

Scribd : https://tinyurl.com/2w3vjs99

DOI : https://doi.org/10.38124/ijisrt/26jun1045

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Abstract : Diabetic foot infection is a serious complication associated with diabetes. The condition affects the quality of life in patients of all classes, races, and ages. If left untreated, may lead to gangrene, osteomyelitis, and amputation. This study was conducted to ascertain the antibiotic susceptibility profiles of bacteria from diabetic foot infections (DFIs) in Enugu. Demographical and clinical history data were gathered using structured questionnaire. Diabetic wound samples were collected and analysed using standard microbiological procedures. Isolation and identification of bacterial species were based on cultural morphology, microscopy, and biochemical tests. Antibiotic susceptibility was assessed on eight antibiotic agents: amoxycillin/clavulanic acid, nitrofurantoin, cefoxitin, imipenem, gentamicin, ciprofloxacin, colistin sulphate, and cotrimoxazole following the Kirby-Bauer disc diffusion technique and CLSI guidelines.

Keywords : Diabetes, Diabetic Foot Infection, Antibiotic Resistance, Foot Ulcer, Polymicrobial.

References :

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Diabetic foot infection is a serious complication associated with diabetes. The condition affects the quality of life in patients of all classes, races, and ages. If left untreated, may lead to gangrene, osteomyelitis, and amputation. This study was conducted to ascertain the antibiotic susceptibility profiles of bacteria from diabetic foot infections (DFIs) in Enugu. Demographical and clinical history data were gathered using structured questionnaire. Diabetic wound samples were collected and analysed using standard microbiological procedures. Isolation and identification of bacterial species were based on cultural morphology, microscopy, and biochemical tests. Antibiotic susceptibility was assessed on eight antibiotic agents: amoxycillin/clavulanic acid, nitrofurantoin, cefoxitin, imipenem, gentamicin, ciprofloxacin, colistin sulphate, and cotrimoxazole following the Kirby-Bauer disc diffusion technique and CLSI guidelines.

Keywords : Diabetes, Diabetic Foot Infection, Antibiotic Resistance, Foot Ulcer, Polymicrobial.

Paper Submission Last Date
31 - July - 2026

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