Authors :
Pratha Patil; Umra Rehman; Nisha Prabhakar; Sarvar Jahan
Volume/Issue :
Volume 11 - 2026, Issue 4 - April
Google Scholar :
https://tinyurl.com/cb4k9fe4
Scribd :
https://tinyurl.com/yrd9j3e8
DOI :
https://doi.org/10.38124/ijisrt/26apr2125
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Many people have died from infectious diseases, which has made the public more aware of how dangerous these
illnesses can be, and this has led to more global efforts to research antimicrobial treatments. However, the demand and use
of antibiotics have led to an increase in antibiotic levels within natural ecosystems. Natural selection and adaptation caused
changes in bacterial genes that make them resistant to antibiotics. The spread of antibiotic resistance genes in ecosystems
caused the rise of bacteria that are resistant to antibiotics, which has led to many different antibiotic-resistant diseases
around the world. This paper gives a general look at how antibiotics were discovered, the methods used to find new
antibiotics, and the steps involved in making antibiotics on a large scale in industry. Also, there has been a review of how
antibiotic-resistant bacteria are becoming more common and the effects of antibiotics on the environment, along with some
recommendations provided. The topic of antibiotic resistance has also been looked at from an ecological point of view. New
drug development appears to be the main requirement now to control microbes that are no longer responding to existing
drugs.
References :
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- Sikiru AO, Chima OK, Otunba M, Gaffar O, Adenuga AA. Navigating the Regulatory Trilemma-A Framework for Balancing US Tariffs, EU ESG Directives, and Cross-Border Capital Controls. Engineering and Technology Journal. 2025;10(08):6437-56.
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Many people have died from infectious diseases, which has made the public more aware of how dangerous these
illnesses can be, and this has led to more global efforts to research antimicrobial treatments. However, the demand and use
of antibiotics have led to an increase in antibiotic levels within natural ecosystems. Natural selection and adaptation caused
changes in bacterial genes that make them resistant to antibiotics. The spread of antibiotic resistance genes in ecosystems
caused the rise of bacteria that are resistant to antibiotics, which has led to many different antibiotic-resistant diseases
around the world. This paper gives a general look at how antibiotics were discovered, the methods used to find new
antibiotics, and the steps involved in making antibiotics on a large scale in industry. Also, there has been a review of how
antibiotic-resistant bacteria are becoming more common and the effects of antibiotics on the environment, along with some
recommendations provided. The topic of antibiotic resistance has also been looked at from an ecological point of view. New
drug development appears to be the main requirement now to control microbes that are no longer responding to existing
drugs.