Authors :
Richa Sharma; D.N.Choudhary
Volume/Issue :
Volume 9 - 2024, Issue 1 - January
Google Scholar :
http://tinyurl.com/4rvht3zs
Scribd :
http://tinyurl.com/42svhhjt
DOI :
https://doi.org/10.5281/zenodo.10613167
Abstract :
Plants have long been utilized to treat a
variety of illnesses. Search for male antifertility factor of
medicinal plants remained a potential area of
investigation. The present investigation was aimed to
study the effect of oral administration of two medicinal
plants , Melia azedarach (leaf) and Momordica
dioica(fruit) at a dose of 100mg/kg body weight for 21
days on reproductive organs of male albino rats. Body
weight, Reproductive Organ weight , Fructose content
in Coagulating gland(CG), Acid phosphatase activity in
Ventral prostate(VP), Total protein in Seminal
vesicle(SV) were investigated in both control and treated
groups. Histology of testis in treated rats showed
degenerative changes in the seminiferous tubules. The
decrease in sperm count with wider lumen, organ weight,
fructose content in CG, protein content in SV, suggesting
the antifertility activity in both tested plants. Corpus
luteal sites, Implantation sites, and Litter size were also
found significantly reduced.
Keywords :
Antifertility, Biochemical Parameters, Melia Azedarach, Momordicadioica, Sperm Count, Testis.
Plants have long been utilized to treat a
variety of illnesses. Search for male antifertility factor of
medicinal plants remained a potential area of
investigation. The present investigation was aimed to
study the effect of oral administration of two medicinal
plants , Melia azedarach (leaf) and Momordica
dioica(fruit) at a dose of 100mg/kg body weight for 21
days on reproductive organs of male albino rats. Body
weight, Reproductive Organ weight , Fructose content
in Coagulating gland(CG), Acid phosphatase activity in
Ventral prostate(VP), Total protein in Seminal
vesicle(SV) were investigated in both control and treated
groups. Histology of testis in treated rats showed
degenerative changes in the seminiferous tubules. The
decrease in sperm count with wider lumen, organ weight,
fructose content in CG, protein content in SV, suggesting
the antifertility activity in both tested plants. Corpus
luteal sites, Implantation sites, and Litter size were also
found significantly reduced.
Keywords :
Antifertility, Biochemical Parameters, Melia Azedarach, Momordicadioica, Sperm Count, Testis.
