Health systems are facing the COVID-19 pandemic forcing health professionals to have labor and social changes such as telework Objective: to determine the level of anxiety and depression in health professionals dedicated to teleworking the General Hospital of the IESS the City of Machala. Methodology: A quantitative, descriptive and non-experimental crosssectional cohort study was carried out. Validated questionnaires were used: state-trait anxiety, STAI (1) in the Spanish version, the IDER, or Spielberger's StateTrait Depression Inventory (2) in the Spanish version of TEA EDICIONES. Sample: it was 95 professionals who carried out telework in the period from May to November 2020. Results: it was identified that the population that carried out telework were Nursing professionals, likewise, some trait of anxiety was identified during teleworking. Conclusions

Keywords : Anxiety, Depression, Nursing, Health, Telework