Research with titled “Pre-experimental study to assess the effectiveness of Structured Teaching Programme on knowledge of HPV infection and vaccination among adolescent’s girls at selected school in Greater Noida, UP’’ METHODOLOGY: A Quantitative research approach was used and the pre-experimental one group pre-test and post-test research design was adopted for the present study. The target population for the study was adolescent girls, Sample size was 60. Sampling Technique for the study was Purposive Sampling Technique. RESULTS: In this research study that the majority of samples were 54[54.5%]in age group 13- 15 years , sample Pre-test finding of the study revealed that around 48.5% were having poor level of knowledge, about 12.1% of participants found with average level of knowledge and no one particiants had good level of knowledge. Post-test finding of the study revealed that around 51.5% of them were having average level of knowledge; about 3.0% of them having good level of knowledge and 5.1% of them had poor level of knowledge. During Comparison of knowledge score of study reveals that, there was statistically significant difference noted in the mean knowledge scores of adolescents a girl regarding HPV Infection and Vaccination in pre-test and post- test(p<0.005). Conclusion It shows that the intervention was effective in improving the knowledge of adolescent’s girls.

Keywords : HPV Infection, Vaccination.