Authors : Dr. Junior Sundresh N.; Dhanushya N.; Lokeshwari S.

Volume/Issue : Volume 10 - 2025, Issue 8 - August

Google Scholar : https://tinyurl.com/3w68yyxj

Scribd : https://tinyurl.com/43w62skw

DOI : https://doi.org/10.38124/ijisrt/25aug632

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Abstract : Background: Cellulitis, a common bacterial skin condition, requires prompt treatment. This study analyzed risk factors and treatment outcomes of patients over six months.  Methods: A prospective observational study was conducted at Government Cuddalore Medical College and Hospital for a period of six months (November 2024-April 2025). Fifty adult patients with diagnosed cellulitis were included. Data on demographics, comorbidities, use of antibiotics, complications, and hospital stay was reviewed.  Results: Most patients were male and in the 41–50 age group. Diabetes mellitus was the most common comorbid condition. No significant link was found between the type of antibiotic and treatment outcomes, but a strong association (p < 0.001) was found between the number of comorbid conditions and recurrence, complications, and duration of hospital stay.  Conclusion: Comorbid conditions significantly affect treatment outcomes in cellulitis. Effective management should include treatment with antibiotics, as well as addressing underlying health issues.

Keywords : Cellulitis, Risk Factors, Treatment Outcomes, Complications.

References :

1. Baddour, L. M., Tleyjeh, I. M., & Wilson, W. R. (2023). Cellulitis and erysipelas: Clinical features and diagnosis. UpToDate. Retrieved August 2025, from https://www.uptodate.com
2. Centers for Disease Control and Prevention. (2022). Group A Streptococcal (GAS) disease: Cellulitis. https://www.cdc.gov/groupastrep/diseases-hcp/cellulitis.html
3. Collazos, J., de la Fuente, B., García, A., Gómez, H., Menéndez, C., Enríquez, H., ... & Asensi, V. (2018). Cellulitis in adult patients: a large, multicenter, observational, prospective study of 606 episodes and analysis of the factors related to the response to treatment. PloS one, 13(9), e0204036.
4. Cranendonk, D. R., Lavrijsen, A. P. M., Prins, J. M., & Wiersinga, W. J. (2017). Cellulitis: current insights into pathophysiology and clinical management. Neth J Med, 75(9), 366-378.
5. Mandell, G. L., Bennett, J. E., & Dolin, R. (2020). Mandell, Douglas, and Bennett’s principles and practice of infectious diseases (9th ed.). Elsevier.
6. Mayo Clinic Staff. (2023). Cellulitis – Symptoms and causes. Mayo Clinic. Retrieved August 2025, from https://www.mayoclinic.org/diseases-conditions/cellulitis/symptoms-causes/syc-20370762
7. National Institute for Health and Care Excellence. (2019). Cellulitis and erysipelas: Antimicrobial prescribing (NICE guideline NG141). https://www.nice.org.uk/guidance/ng141
8. Ong, B. S., Dotel, R., & Ngian, V. J. J. (2022). Recurrent cellulitis: who is at risk and how effective is antibiotic prophylaxis?. International Journal of General Medicine, 15, 6561.
9. Simonsen, S. E., Van Orman, E. R., Hatch, B. E., Jones, S. S., Gren, L. H., Hegmann, K. T., & Lyon, J. L. (2006). Cellulitis incidence in a defined population. Epidemiology & Infection, 134(2), 293-299.
10. Stevens, D. L., Bisno, A. L., Chambers, H. F., Dellinger, E. P., Goldstein, E. J., Gorbach, S. L., ... & Wade, J. C. (2014). Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clinical infectious diseases, 59(2), e10-e52.