Authors :
Lidya Yudith Priskila; Rina Agustina; Ratna Djuwita; Inge Permadhi; Fiastuti Witjaksono; Murdani Abdullah; Erfi Prafiantin
Volume/Issue :
Volume 6 - 2021, Issue 11 - November
Google Scholar :
http://bitly.ws/gu88
Scribd :
https://bit.ly/3q4a7G0
Abstract :
Accumulating evidence identifies dietary intake
may trigger chronic low-grade inflammation as potential
mechanisms contributing to insulin resistance. However,
studies regarding dietary inflammatory were inconsistent.
An analysis of diet quality using dietary inflammatory
index (DII) was conducted to investigate whether
individual nutrition intake is proinflammation or antiinflammation. The objective of this study was to
understand the association between DII score and TNF-α
in the normoweight and obese group. A cross-sectional
study comprised 210 Indonesian adults in Jakarta. DII
scores derived from two days of food recall were calculated
based on 40 nutrients and food components, then serum
TNF-α were measured using ELISA. Our data indicate a
more proinflammatory diet, reflected by higher DII scores,
was slightly higher in the obese group than the
normoweight group (p=0,407). The overall DII score was
not associated with serum TNF-α after adjustment for
covariates (ß=0,001, p=0,895). However, when the DII
score was classified into normoweight and obese group, the
DII score in the normoweight group was significantly
associated with serum TNF-α after adjustment for
covariates (ß= 0,013, p=0,036), but not in the obese group.
In conclusion, a positive association between DII score and
serum TNF-α in the normoweight group level suggests that
the diet's inflammatory properties regulate adipose tissue
inflammation.
Keywords :
Dietary quality, dietary inflammatory score, lowgrade inflammation, obesity, TNF-α
Accumulating evidence identifies dietary intake
may trigger chronic low-grade inflammation as potential
mechanisms contributing to insulin resistance. However,
studies regarding dietary inflammatory were inconsistent.
An analysis of diet quality using dietary inflammatory
index (DII) was conducted to investigate whether
individual nutrition intake is proinflammation or antiinflammation. The objective of this study was to
understand the association between DII score and TNF-α
in the normoweight and obese group. A cross-sectional
study comprised 210 Indonesian adults in Jakarta. DII
scores derived from two days of food recall were calculated
based on 40 nutrients and food components, then serum
TNF-α were measured using ELISA. Our data indicate a
more proinflammatory diet, reflected by higher DII scores,
was slightly higher in the obese group than the
normoweight group (p=0,407). The overall DII score was
not associated with serum TNF-α after adjustment for
covariates (ß=0,001, p=0,895). However, when the DII
score was classified into normoweight and obese group, the
DII score in the normoweight group was significantly
associated with serum TNF-α after adjustment for
covariates (ß= 0,013, p=0,036), but not in the obese group.
In conclusion, a positive association between DII score and
serum TNF-α in the normoweight group level suggests that
the diet's inflammatory properties regulate adipose tissue
inflammation.
Keywords :
Dietary quality, dietary inflammatory score, lowgrade inflammation, obesity, TNF-α