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Atypical Axillary Nodal Spread in Lung Carcinoma: Radiologic Insights from a Rare Case


Authors : Dr. Perugu Lakshmi Lavanya; Dr. Bhamidipaty Kanaka Durga Prasad; Dr. Rokkam Sasidhar

Volume/Issue : Volume 11 - 2026, Issue 7 - July


Google Scholar : https://tinyurl.com/bd9fvc6n

Scribd : https://tinyurl.com/5dkr5jv6

DOI : https://doi.org/10.38124/ijisrt/26jul931

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Abstract : Lung squamous cell carcinoma (SCC), a major subtype of non-small cell lung cancer (NSCLC), typically metastasizes to the brain, bone, adrenal glands, and liver. Axillary lymph node metastasis (ALNM) is exceedingly rare and often mimics breast malignancy, risking misdiagnosis. We present a rare case of a 74-year-old chronic smoker with isolated ALNM, brain, spinal, and retroperitoneal metastases without mediastinal involvement. Diagnosis was confirmed through ultrasound, mammography, contrast-enhanced CT (CECT), MRI, and fine-needle aspiration cytology (FNAC). Conclusion: This case underscores the need for radiologic vigilance to identify atypical metastatic patterns and avoid diagnostic errors.

Keywords : Axillary Lymph Node Metastasis, Lung Cancer, Brain Metastasis, Radiologic Correlation.

References :

  1. Siegel RL, Miller KD, Wagle NS, Jemal A. Cancer statistics, 2024. CA Cancer J Clin 2024;74(1):12-49.
  2. Riquet M, Le Pimpec-Barthes F, Danel C. Axillary lymph node metastases from bronchogenic carcinoma. Ann Thorac Surg 1998;66(3):920-22.
  3. Satoh H, Ishikawa H, Kagohashi K, Kurishima K, Sekizawa K. Axillary lymph node metastasis in lung cancer. Med Oncol 2009;26(2):147-50.
  4. Detterbeck FC, Boffa DJ, Kim AW, Tanoue LT. The eighth edition lung cancer stage classification. Chest 2017;151(1):193-203.
  5. Ochsner A, DeBakey M. Significance of metastasis in primary carcinomaof the lungs: Report of Two Cases With Unusual Site of Metastasis Journal of Th oracicSurgeryVolume 11, Issue 4, April 1942, Pages 357-387.
  6. SH McEvoy , DF Halpenny.  Investigation of patterns of nodal metastases in BRAF mutant lung cancer. Lung Cancer. 2017 Mar 1;108:62–65
  7. Mercedes L Dalurzo ,Testing for EGFR Mutations and ALK Rearrangements in Advanced Non-Small-Cell Lung Cancer: Considerations for Countries in Emerging Markets. Onco Targets Ther. 2021 Sep 1;14:4671–4692. doi: 10.2147/OTT.S313669
  8. Xiayao Diao , Chao Guo . Lymphatic metastasis in non‐small cell lung cancer: recent discoveries and novel therapeutic targets.Cancer Commun (Lond). 2022 Nov 9;42(12):1403-1406
  9. Narjust Duma , Rafael Santana-Davila.Non-Small Cell Lung Cancer: Epidemiology, Screening, Diagnosis, and Treatment. Mayo Clin Proc. 2019 Aug;94(8):1623-1640.
  10. Reck M, Rabe KF. Precision diagnosis and treatment for advanced non-small-cell lung cancer. N Engl J Med 2023;389(8):738-51.

Lung squamous cell carcinoma (SCC), a major subtype of non-small cell lung cancer (NSCLC), typically metastasizes to the brain, bone, adrenal glands, and liver. Axillary lymph node metastasis (ALNM) is exceedingly rare and often mimics breast malignancy, risking misdiagnosis. We present a rare case of a 74-year-old chronic smoker with isolated ALNM, brain, spinal, and retroperitoneal metastases without mediastinal involvement. Diagnosis was confirmed through ultrasound, mammography, contrast-enhanced CT (CECT), MRI, and fine-needle aspiration cytology (FNAC). Conclusion: This case underscores the need for radiologic vigilance to identify atypical metastatic patterns and avoid diagnostic errors.

Keywords : Axillary Lymph Node Metastasis, Lung Cancer, Brain Metastasis, Radiologic Correlation.

Paper Submission Last Date
31 - August - 2026

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