Authors : Soumya Ranjan Mohanty; Mallavarapu Manisha; Manish Kumar

Volume/Issue : Volume 10 - 2025, Issue 7 - July

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DOI : https://doi.org/10.38124/ijisrt/25jul1587

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Abstract : Cushing’s syndrome is a rare disorder with varied clinical manifestations, often leading to delayed diagnosis. We report a case of a 35-year-old woman presenting with worsening dyspnea, secondary amenorrhea, and proximal muscle weakness. Initial evaluation revealed congestive heart failure and poorly controlled diabetes. Further endocrinological workup confirmed ACTH-independent Cushing’s syndrome secondary to an adrenal adenoma. Following surgical adrenalectomy, the patient showed significant clinical improvement. This case highlights the importance of a high index of suspicion for endocrine disorders in patients with systemic symptoms like heart failure and myopathy.

Keywords : Cushing’s Syndrome, ACTH-Independent, Adrenal Adenoma, Proximal Myopathy, Secondary Amenorrhea, Congestive Cardiac Failure.

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