Augmenting Effect of Hyperthermia in Neoadjuvant Chemotherapy for Advanced Breast Cancer – A Case Report

Authors : Suresh Gajendran; Devi sri Rajaraman; Damodara kumaran; Ragasudha Veeramani; Mustaq Ahamed

Volume/Issue : Volume 8 - 2023, Issue 8 - August

Google Scholar :

Scribd :


Background: Locally advanced breast cancer encompasses a heterogeneous collection of breast neoplasms, constituting approximately 10 to 20% of newly diagnosed breast cancer cases annually. The patient often presents with an ulcerative lesion in the breast with foul-smelling or bloody discharge associated with supra clavicular lymphadenopathy and axillary lymphadenopathy. Case report: In this study, we reported a case of a 48-year-old female with complaints of an ulcerated lesion with severe pain over the right breast and foul-smelling serosanguinous discharge from the ulcer. Later, it was diagnosed as a case of carcinoma of the right breast stage cT4bN1Mx. The patient was given neoadjuvant chemotherapy and three sessions of hyperthermia per week for 22 sessions. Results: The tumor responded well to neoadjuvant chemotherapy and hyperthermia, converting the inoperable tumor into an operable tumor. Conclusion: Combined neoadjuvant chemotherapy and hyperthermia significantly reduce the size of locally advanced breast cancer by converting it into an operable one, and there was a reduction in pain over the ulcer, improving the patient's quality of life.

Keywords : Breast Cancer, Chemosensitizer, Chemotherapy, Hyperthermia, Neoplasm.


Paper Submission Last Date
31 - December - 2023

Paper Review Notification
In 1-2 Days

Paper Publishing
In 2-3 Days

Video Explanation for Published paper

Never miss an update from Papermashup

Get notified about the latest tutorials and downloads.

Subscribe by Email

Get alerts directly into your inbox after each post and stay updated.

Subscribe by RSS

Add our RSS to your feedreader to get regular updates from us.