Ayurvedic Management of Osteoporosis W.S.R. to Asthikshaya- A Pilot Study


Authors : Dr. Janhavi Meshram; Dr. Aarti Bhandule; Dr. Hema Boryale; Dr. Naresh Jain

Volume/Issue : Volume 9 - 2024, Issue 10 - October


Google Scholar : https://tinyurl.com/4nbtrdym

Scribd : https://tinyurl.com/3vk92c9p

DOI : https://doi.org/10.38124/ijisrt/IJISRT24OCT1527

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Osteoporosis is marked by a substantial decrease in bone mass and a deterioration of the microarchitecture of bone tissue, which increases the risk of fractures. This condition often goes unnoticed until a fracture occurs, which is why it is often referred to as a "silent disease". Asthikshaya is an Ayurvedic term that refers to the depletion, degeneration, or weakening of Asthi Dhatu (bone tissue). It occurs when there is an insufficient formation or nourishment of the Asthi Dhatu, leading to a decrease in bone density and strength. This condition can manifest as bone weakness, brittle nails and teeth, hair loss, joint pain, and a greater risk of fractures or bone-related disorders, such as osteoporosis. Worldwide, an osteoporotic fracture happens every three seconds, significantly impacting individuals and disrupting their lives. By the age of 50, the probability of sustaining a fracture is one in three for women and one in five for men. The incidence of hip fractures in women is greater than the combined risk of breast, ovarian, and uterine cancers, while for men, the risk of hip fractures exceeds that of prostate cancer. Alarmingly, about 50% of individuals who experience an initial osteoporotic fracture will suffer additional fractures, with the risk escalating with each subsequent incident. In the present clinical study, 15 clinically proven patients of Osteoporosis were treated with Asthiposhtika Vati to evaluate its therapeutic effectiveness. Ayurvedic parameters (Lakshanas) of Asthikshaya were used as subjective parameters to assess the effectiveness of the drug. Statistical analysis was conducted using the t-test, and the results were encouraging, indicating that Asthiposhtika Vati (Anubhoot yoga) is effective in managing osteoporosis, thereby exploring various aspects of this clinical condition.

Keywords : Asthikshaya, Osteoporosis, Asthiposhtika Vati, Anubhoot Yoga.

References :

  1. Charaka Samhita with Charaka Chandrika Hindi Commentary by Dr. Brahmanand Tripathi, Chaukhamba Surbharati Prakashan, Varanasi - 221001
  2. Sushruta Samhita with Sushrut Vimarshini Hindi commentary by Dr. Anant Ram Sharma, Chaukhamba Surbharati Prakashan, Varanasi – 221001
  3. Ashtanga Hridyam with Nirmala Hindi commentary by Dr. Brahmanand Tripathi, Chaukhamba Sanskrit Pratishthan, Delhi – 110007
  4. Bhavaparkasha Nighantu commentary by Padmshri Prof. K. C. Chunekar 2015 Chaukhambha Bharati Academy Varanasi-221001
  5. Dravyaguna Vigyan by Prof. P. V. Sharma, Chaukhamba Bharati Academy, Varanasi 221001
  6. Rasatantrasaar & Siddhaprayog Sangraha, Krishna Gopal Ayurved Bhawan, Ajmer, Rajasthan 305408
  7. P. J Mehta’s Practical Medicine, 22nd edition.
  8. Harrison’s Principles of Internal Medicine, 14th Ed., New Delhi, McGraw Hill, Health Professions Division 1998; 2: 2247-53.
  9. Formulation of Polyherbomineral matrices for treatment of Osteoporosis, Department of Pharmaceutics, Government College of Pharmacy, Kathora Naka, Amravati – 444 604, Maharashtra, India.

Osteoporosis is marked by a substantial decrease in bone mass and a deterioration of the microarchitecture of bone tissue, which increases the risk of fractures. This condition often goes unnoticed until a fracture occurs, which is why it is often referred to as a "silent disease". Asthikshaya is an Ayurvedic term that refers to the depletion, degeneration, or weakening of Asthi Dhatu (bone tissue). It occurs when there is an insufficient formation or nourishment of the Asthi Dhatu, leading to a decrease in bone density and strength. This condition can manifest as bone weakness, brittle nails and teeth, hair loss, joint pain, and a greater risk of fractures or bone-related disorders, such as osteoporosis. Worldwide, an osteoporotic fracture happens every three seconds, significantly impacting individuals and disrupting their lives. By the age of 50, the probability of sustaining a fracture is one in three for women and one in five for men. The incidence of hip fractures in women is greater than the combined risk of breast, ovarian, and uterine cancers, while for men, the risk of hip fractures exceeds that of prostate cancer. Alarmingly, about 50% of individuals who experience an initial osteoporotic fracture will suffer additional fractures, with the risk escalating with each subsequent incident. In the present clinical study, 15 clinically proven patients of Osteoporosis were treated with Asthiposhtika Vati to evaluate its therapeutic effectiveness. Ayurvedic parameters (Lakshanas) of Asthikshaya were used as subjective parameters to assess the effectiveness of the drug. Statistical analysis was conducted using the t-test, and the results were encouraging, indicating that Asthiposhtika Vati (Anubhoot yoga) is effective in managing osteoporosis, thereby exploring various aspects of this clinical condition.

Keywords : Asthikshaya, Osteoporosis, Asthiposhtika Vati, Anubhoot Yoga.

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