The increased risk of bacteriuria in pregnancy poses a threat to the mother and fetus, some of which include preterm labor and pyelonephritis. Screening for bacteriuria in pregnant women has been included as one of the most cost effective strategies for achieving the Millennium Development Goals for health in developing countries. Findings: The overall prevalence of bacteriuria among pregnant women was 26.2%. It was higher in pregnant women with symptoms of acute UTI (16.7%) than in those without symptoms (9.5%). E. coli (26.7%), CoNS (26.7%), Klebsiella pneumoniae (13.3%), Proteus mirabilis (10%) and group D streptococci (10%) were common uropathogens. Pyuria was the strongest predictor of bacteriuria. However, there was no statistically significant risk factor of bacteriuria thus, limiting the possibility of targeted screening. GNB were least resistant to gentamicin and ciprofloxacin while the gram positives showed least resistance to cefuroxime. All isolates were susceptible to nitrofurantoin. Conclusion: This study reveals that bacteriuria occurs in one of every four pregnant women and ASB occurs in one of every ten pregnant women. This is of great concern since bacteruiria is harmful to both mother and fetus. However, 15 isolates showed resistance to at least one antibiotic of the beta lactam class (50%) and 86.7% of isolated uropathogens were resistant to at least one antibiotic hence, we fail to reject the null hypothesis: Resistant bacteria are the most frequent cause of bacteriuria in pregnancy

Keywords : Bacteriuria, ASB, Uropathogens, Antibiotic Resistance