⚠ Official Notice: www.ijisrt.com is the official website of the International Journal of Innovative Science and Research Technology (IJISRT) Journal for research paper submission and publication. Please beware of fake or duplicate websites using the IJISRT name.



Beyond the Predicted Profile: Clinical Validity of Artificial Intelligence Based Facial Outcomes in Orthodontics


Authors : Dr. Utkarsha U. Chavan; Dr. Chanamallappa R. Ganiger; Dr. Renuka Pawar; Dr. Sandesh Phaphe; Dr. Yusuf Ronad; Dr. Pratap Mane; Dr. Seema Patil

Volume/Issue : Volume 11 - 2026, Issue 10 - October


Google Scholar : https://tinyurl.com/2ehssa52

DOI : https://doi.org/10.38124/ijisrt/26Oct1554

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Introduction and Background: Artificial intelligence is increasingly being explored to predict facial soft tissue outcomes following orthodontic treatment. AI systems may aid in treatment expectations and profile prediction in patients. However, it is important to determine that the predicted outcome is not simply visually accurate.  Review: This narrative review discusses the differences between geometric accuracy, visual accuracy and clinical utility when using AI systems to predict post-orthodontic facial outcomes. Previous research has focused on using artificial neural networks, convolutional neural networks, deep neural networks and conditional generative adversarial networks. More recently, models have used machine learning with incisors and facial measurements, generative networks for lateral profile prediction and prediction from facial frontal photographs. Across all studies there has been varying success depending on the imaging type, region of interest, patient population and the type of measurement used. Difficulties were seen with predicting lower lip and chin areas. Additionally, even when there has been good success with numbers there has not been improved treatment decisions or outcomes.  Conclusions: Using AI to predict facial outcomes is an emerging field which may be beneficial. However, the clinical validity of the outcomes should be investigated. Future research should ensure independent validation occurs, measurement of error within each anatomical region, patient and clinician evaluation, clear communication of uncertainty and evidence of clinical decision making. Until this evidence is present the outcomes should be used as support.

Keywords : Artificial Intelligence, Orthodontics, Facial Profile, Soft Tissue Prediction, Deep Learning, Generative Artificial Intelligence, Treatment Planning.

References :

  1. Zhu J, Yang Y, Wong HM. Development and accuracy of artificial intelligence-generated prediction of facial changes in orthodontic treatment: a scoping review. J Zhejiang Univ Sci B. 2023;24:974-984. doi: 10.1631/jzus.B2300244.
  2. Tanikawa C, Yamashiro T. Development of novel artificial intelligence systems to predict facial morphology after orthognathic surgery and orthodontic treatment in Japanese patients. Sci Rep. 2021;11:15853. doi: 10.1038/s41598-021-95002-w.
  3. Park YS, Choi JH, Kim Y, et al. Deep learning-based prediction of the 3D postorthodontic facial changes. J Dent Res. 2022;101:1372-1379. doi: 10.1177/00220345221106676.
  4. Peng J, Zhang Y, Zheng M, et al. Predicting changes of incisor and facial profile following orthodontic treatment: a machine learning approach. Prog Orthod. 2025;21:22. doi: 10.1186/s13005-025-00499-5.
  5. Research of orthodontic soft tissue profile prediction based on conditional generative adversarial networks. J Dent. 2025;154:105570. doi: 10.1016/j.jdent.2025.105570.
  6. Cho SJ, et al. Orthodontic treatment outcome predictive performance differences between artificial intelligence and conventional methods. Angle Orthod. 2024;94:557-565. doi: 10.2319/111823-767.1.
  7. Facial soft-tissue shape changes after fixed edgewise treatment with premolar extraction in individual artificial-intelligence-classified facial profile patterns. BMC Oral Health. 2024. doi: 10.1186/s12903-024-04512-2.
  8. Rashmi R, Tripathi T, Jerripothula KR, Rai P, Sardana R. Predictive modeling of soft tissue changes after orthodontic treatment with premolar extractions using frontal facial photographs. Am J Orthod Dentofacial Orthop. 2026;170:357-366. doi: 10.1016/j.ajodo.2026.03.014.
  9. Prediction of facial profiles following orthodontic treatment in adult Class III patients using deep neural networks with feature fusion. J Dent. 2026;169:106627. doi: 10.1016/j.jdent.2026.106627.

Introduction and Background: Artificial intelligence is increasingly being explored to predict facial soft tissue outcomes following orthodontic treatment. AI systems may aid in treatment expectations and profile prediction in patients. However, it is important to determine that the predicted outcome is not simply visually accurate.  Review: This narrative review discusses the differences between geometric accuracy, visual accuracy and clinical utility when using AI systems to predict post-orthodontic facial outcomes. Previous research has focused on using artificial neural networks, convolutional neural networks, deep neural networks and conditional generative adversarial networks. More recently, models have used machine learning with incisors and facial measurements, generative networks for lateral profile prediction and prediction from facial frontal photographs. Across all studies there has been varying success depending on the imaging type, region of interest, patient population and the type of measurement used. Difficulties were seen with predicting lower lip and chin areas. Additionally, even when there has been good success with numbers there has not been improved treatment decisions or outcomes.  Conclusions: Using AI to predict facial outcomes is an emerging field which may be beneficial. However, the clinical validity of the outcomes should be investigated. Future research should ensure independent validation occurs, measurement of error within each anatomical region, patient and clinician evaluation, clear communication of uncertainty and evidence of clinical decision making. Until this evidence is present the outcomes should be used as support.

Keywords : Artificial Intelligence, Orthodontics, Facial Profile, Soft Tissue Prediction, Deep Learning, Generative Artificial Intelligence, Treatment Planning.

Paper Submission Last Date
30 - November - 2026

SUBMIT YOUR PAPER CALL FOR PAPERS
Video Explanation for Published paper

Never miss an update from Papermashup

Get notified about the latest tutorials and downloads.

Subscribe by Email

Get alerts directly into your inbox after each post and stay updated.
Subscribe
OR

Subscribe by RSS

Add our RSS to your feedreader to get regular updates from us.
Subscribe