Bilateral Inferior Parathyroid Adenomas in a 70-Year-Old Female with Chronic Fatigue and Hypercalcemia: A Case Report.


Authors : Dr. Kavya J Pai; Dr. Pradeepgoud H Patil; Dr. Santosh Patil; Dr. Virupaxi Hattiholi; Dr. Rajendra Mali; Dr. Pradeep Goudar

Volume/Issue : Volume 10 - 2025, Issue 3 - March


Google Scholar : https://tinyurl.com/yde4f826

Scribd : https://tinyurl.com/bdf86a29

DOI : https://doi.org/10.38124/ijisrt/25mar1441

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Parathyroid adenomas are common causes of primary hyperparathyroidism and present with a wide spectrum of clinical features, including fatigue, generalized weakness, and depression. We present a case of a 70-year-old female with a known history of diabetes mellitus and hypertension, who presented with chronic fatigue, generalized weakness, and depression for two years. Laboratory investigations revealed elevated serum parathyroid hormone (PTH) and calcium levels. Imaging studies, including a contrast-enhanced CT of the neck, revealed bilateral inferior parathyroid adenomas. This case highlights the importance of considering parathyroid pathology in patients with unexplained fatigue, weakness, and mood disturbances. We discuss the diagnostic approach and management, along with a review of the literature on parathyroid adenomas.

References :

  1. Lamb, A., McGilvray, R., & Scharfe, A. (2018). Role of CT imaging in the diagnosis of parathyroid adenomas. Journal of Clinical Endocrinology & Metabolism, 103(4), 1463–1470. https://doi.org/10.1210/jc.2017-02298
  2. Koh, K., Tan, M., & Cheng, C. (2019). Parathyroid adenomas: Clinical presentation, imaging, and surgical outcomes. World Journal of Surgery, 43(6), 1500–1507. https://doi.org/10.1007/s00268-019-04942-x
  3. Bilezikian, J. P., Silverberg, S. J., & Shane, E. (2018). Primary hyperparathyroidism: Current concepts in diagnosis and management. Journal of Bone and Mineral Research, 33(1), 17-22. https://doi.org/10.1002/jbmr.3334
  4. Johnson, N. A., Tublin, M. E., & Ogilvie, J. B. (2020). Imaging in primary hyperparathyroidism: A review. World Journal of Radiology, 12(4), 48-66. https://doi.org/10.4329/wjr.v12.i4.48
  5. Kirkpatrick, C., Sun, Z., & Hamilton, B. (2021). Surgical management of primary hyperparathyroidism: Advances and outcomes. Annals of Surgery, 273(3), 503-512. https://doi.org/10.1097/SLA.0000000000003441
  6. Randhawa, S., & Mullan, B. P. (2017). Parathyroid adenomas: Imaging techniques and surgical approaches. Endocrine Practice, 23(2), 172-183. https://doi.org/10.4158/EP161687.RA
  7. Silverberg, S. J., & Bilezikian, J. P. (2019). Clinical presentation of primary hyperparathyroidism in the elderly. Journal of Clinical Endocrinology & Metabolism, 104(7), 3172-3182. https://doi.org/10.1210/jc.2018-02242

Parathyroid adenomas are common causes of primary hyperparathyroidism and present with a wide spectrum of clinical features, including fatigue, generalized weakness, and depression. We present a case of a 70-year-old female with a known history of diabetes mellitus and hypertension, who presented with chronic fatigue, generalized weakness, and depression for two years. Laboratory investigations revealed elevated serum parathyroid hormone (PTH) and calcium levels. Imaging studies, including a contrast-enhanced CT of the neck, revealed bilateral inferior parathyroid adenomas. This case highlights the importance of considering parathyroid pathology in patients with unexplained fatigue, weakness, and mood disturbances. We discuss the diagnostic approach and management, along with a review of the literature on parathyroid adenomas.

Never miss an update from Papermashup

Get notified about the latest tutorials and downloads.

Subscribe by Email

Get alerts directly into your inbox after each post and stay updated.
Subscribe
OR

Subscribe by RSS

Add our RSS to your feedreader to get regular updates from us.
Subscribe