The irrigation solutions most often used in the
endodontic treatment are NaOCl 2.5% and EDTA 17%.
However, these two irrigation solutions still have
shortcomings. One of the natural ingredients currently
being developed as an irrigation solutions alternative is
Lerak fruit extract. The results showed that the Lerak
fruit (Sapindusrarak DC) extract solution was
antibacterial, antifungal, cleaned root canal smear layer,
and more biocompatible than the NaOCl solution.
F.nucleatumwas the most common bacteria found in teeth
with root canal infections. This study aimed to determine
the effect of Lerak fruit extract in inhibiting the
Fusobacteriumnucleatum development through
hydrophobicity, destructive enzyme expression, and
fracture resistance. This experimental post-test only
Fracture resistance, Fusobacteriumnucleatum, Root canal, Sapindusrarak DC, Virulence.