Cardiotoxic Effect of Aqueous and Alcoholic Crude Extract of some Indigenous Plants on Rana Tigrina (Hoplobatrachus Tigerinus)


Authors : Dr. S. S. Patole

Volume/Issue : Volume 7 - 2022, Issue 3 - March

Google Scholar : https://bit.ly/3IIfn9N

Scribd : https://bit.ly/3M2yrBB

DOI : https://doi.org/10.5281/zenodo.6461449

The therapeutic effects like antimicrobial, insecticidal, larvicidal, Piscicidal, molluscicidal etc of various indigenous plants have been described. In present study, the effects of 10 % aqueous and alcoholic crude extracts of some indigenous plants on heart rate of Rana tigrina were examined in laboratory conditions. However, both aqueous and alcoholic extracts of used plants viz., Acacia concinna, Acorus calamus, Balanites roxburghii, Cestrum nocturnum, Nicotiana tabecum and Sapindus trifoliatus were found to be highly significant as Cardiotoxic plants than remaining plants. Secondly, alcoholic extract was more potent to reduce in heart rate than aqueous extract of same plants. These results therefore seems to support the claim that most of used plants contain saponin and glycosides as an active ingredient in them, they might be cause to decrease rate of heart contraction by inhibiting the cellular SodiumPotassium ATPase pump.

Keywords : Therapeutic, indigenous, antimicrobial, crude extract, Na+ -K +ATPase pump.

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