The therapeutic effects like antimicrobial,
insecticidal, larvicidal, Piscicidal, molluscicidal etc of
various indigenous plants have been described. In
present study, the effects of 10 % aqueous and alcoholic
crude extracts of some indigenous plants on heart rate of
Rana tigrina were examined in laboratory conditions.
However, both aqueous and alcoholic extracts of used
plants viz., Acacia concinna, Acorus calamus, Balanites
roxburghii, Cestrum nocturnum, Nicotiana tabecum and
Sapindus trifoliatus were found to be highly significant as
Cardiotoxic plants than remaining plants. Secondly,
alcoholic extract was more potent to reduce in heart rate
than aqueous extract of same plants. These results
therefore seems to support the claim that most of used
plants contain saponin and glycosides as an active
ingredient in them, they might be cause to decrease rate
of heart contraction by inhibiting the cellular SodiumPotassium ATPase pump.
Keywords : Therapeutic, indigenous, antimicrobial, crude extract, Na+ -K +ATPase pump.