Case report on Bipolar Affective Disorder with Manic Episodes and Chronic Myeloid Leukemia


Authors : Dr. Shaik Khadeer Ahamad; Sanjana Reddy Thota; Deepthi Dara; Rama Rao Tadikonda

Volume/Issue : Volume 9 - 2024, Issue 6 - June

Google Scholar : https://tinyurl.com/yh63fnne

Scribd : https://tinyurl.com/mufr7azt

DOI : https://doi.org/10.38124/ijisrt/IJISRT24JUN070

Abstract : Bipolar affective disorder (bipolar disorder) is a complex illness characterized by periods of severe mood disruption, including manic episodes. Treatment typically involves a combination of medications tailored to the individual's symptoms and needs. Here, we present the case report of a 45-year-old male farmer with bipolar affective disorder and comorbidities, including diabetes mellitus and chronic myeloid leukemia. The patient exhibited symptoms of mania, including irritability, decreased sleep, over talkativeness, delusions of grandiosity and perception, and psychomotor agitation. Treatment with Risperidone, Sodium Valproate, Haloperidol, Promethazine, and Lorazepam resulted in a 25% improvement in symptoms. Despite challenges posed by comorbid illness and past experiences, the patient showed improvement with adherence to medication. This case underscores the importance of tailored treatment approaches in managing bipolar affective disorder and highlights the need for further research to bridge the gap between evidence-based treatment and clinical practice.

Keywords : Bipolar Disorder, Chronic Myeloid Leukemia, Delusion Of Grandiosity, Psychomotor Agitation.

References :

  1. Rowland TA, Marwaha S. Epidemiology and risk factors for bipolar disorder. Ther Adv Psychopharmacol. 2018 Apr 26;8(9):251-269. doi: 10.1177/2045125318769235. PMID: 30181867; PMCID: PMC6116765.
  2. Deepika K. Case Report on Bipolar Affective Disorder: Mania with PsychoticSymptoms. Pon J Nurs 2019;12(2): 50–51.
  3. Mir JA, Mushtaq B, Mushtaq OA. Clinical case report on bipolar affective disorder, mania. IP J Paediatr Nurs Sci 2022;5(1):32-40.
  4. Vieta E, Sanchez-Moreno J. Acute and long-term treatment of mania. Dialogues Clin Neurosci. 2008;10(2):165-79. doi: 10.31887/DCNS.2008.10.2/evieta. PMID: 18689287; PMCID: PMC3181868.
  5. Kanwar, Aditi & Dayanand, Anupama.K & Kumaran, Muthu. (2022). Bipolar Affective Disorder -Mania with Psychotic Symptoms: A Case Study. 3. 164-167. 10.13140/RG.2.2.27310.59207
  6. Bhadra Sharma E., Thomas S., (2023), A Case Study on Bipolar Affective Disorder Current Episode Manic Without Psychotic Symptoms. International Journal of Clinical Case Reports and Reviews. 13(1); DOI: 10.31579/2690-4861/290
  7. Ara, Hosnea & Nahar, Jhunu & Rahman, Wasima & Ahmed, Srijony & Arafat, S M Yasir. (2019). Psychometric Properties of Bangla Young Mania Rating Scale. 28. 44-52.
  8. Licanin, I., Ducic, A., & Masic, I. (2010). Rate of Bipolar Affective Disorder Registered According to Total Pattern of Morbidity at Psychiatry Clinic in Sarajevo from 2006–2008. Materia Socio-Medica, 22(2), 81-84.https://doi.org/10.5455/msm.2010.22.81-84
  9. Bellman, V., Russell, N., Depala, K., Dellenbaugh, A., Desai, S., Vadukapuram, R., Patel, S., & Srinivas, S. (2021). Challenges in Treating Cancer Patients With Unstable Psychiatric Disorder.World Journal of Oncology, 12(5), 137-148.https://doi.org/10.14740/wjon1402
  10. Calkin CV, Gardner DM, Ransom T, Alda M. The relationship between bipolar disorder and type 2 diabetes: more than just co-morbid disorders. Ann Med. 2013 Mar;45(2):171-81. doi: 10.3109/07853890.2012.687835. Epub 2012 May 24. PMID: 22621171.
  11. Pacchiarotti, I., Anmella, G., Colomer, L., & Vieta, E. (2020). How to treat mania. Acta Psychiatrica Scandinavica, 142(3), 173–192.
  12. Vieta, E., & Sanchez-Moreno, J. (2008). Acute and long-term treatment of mania. Dialogues in Clinical Neuroscience, 10(2), 165-179.

Bipolar affective disorder (bipolar disorder) is a complex illness characterized by periods of severe mood disruption, including manic episodes. Treatment typically involves a combination of medications tailored to the individual's symptoms and needs. Here, we present the case report of a 45-year-old male farmer with bipolar affective disorder and comorbidities, including diabetes mellitus and chronic myeloid leukemia. The patient exhibited symptoms of mania, including irritability, decreased sleep, over talkativeness, delusions of grandiosity and perception, and psychomotor agitation. Treatment with Risperidone, Sodium Valproate, Haloperidol, Promethazine, and Lorazepam resulted in a 25% improvement in symptoms. Despite challenges posed by comorbid illness and past experiences, the patient showed improvement with adherence to medication. This case underscores the importance of tailored treatment approaches in managing bipolar affective disorder and highlights the need for further research to bridge the gap between evidence-based treatment and clinical practice.

Keywords : Bipolar Disorder, Chronic Myeloid Leukemia, Delusion Of Grandiosity, Psychomotor Agitation.

Never miss an update from Papermashup

Get notified about the latest tutorials and downloads.

Subscribe by Email

Get alerts directly into your inbox after each post and stay updated.
Subscribe
OR

Subscribe by RSS

Add our RSS to your feedreader to get regular updates from us.
Subscribe