Causes, Severity and Outcome of Neonatal Thrombocytopenia in Hi-Tech Medical College and Hospital, Bhubaneswar


Authors : Dr. Pritam Kumar Sahoo; Dr. Jaya Pandey Mohapatra; Dr. Smruti Dash Mohapatra; Dr. Ipsa Kujur; Dr Manisha Patro; Dr. Jaya Pandey Mohapatra

Volume/Issue : Volume 7 - 2022, Issue 7 - July

Google Scholar : https://bit.ly/3IIfn9N

Scribd : https://bit.ly/3BYYQyt

DOI : https://doi.org/10.5281/zenodo.6987848

Objective: The objective were to study the causes, severity and outcome of thrombocytopenia in neonates admitted to Neonatal Intensive Care Unit in Hi-Tech Medical College and hospital,Bhubaneswar. Method: Prospective randomized controlled trial was done in NICU at Hi-Tech Medical College and Hospital, Bhubaneswar from September 2019 to August 2021. 100 neonates with or developed neonatal thrombocytopenia were involved during study. Result: In this study, out of 100 neonates with thrombocytopenia- 46%( mild thrombocytopenia ), 35%(moderate thrombocytopenia) and 19%( severe thrombocytopenia). 51% had(72hr)early onset neonatal thrombocytopenia and 49% had(72hr)late onsetneonatal thrombocytopenia. Anaemia was the most common risk factor found in mother. Sepsis was found to be commonest cause of thrombocytopenia in neonates. Apnea was the most common symptom. Sepsis, Respiratory Distress Syndrome (RDS) and Necrotising Enterocolitis(NEC) were the cause of mortality.Sepsis was thecommonest cause of death followed by RDS and NEC. Conclusion: In neonates, thrombocytopenia is a treatable condition. It shouid identify the neonates at risk and initiate platelet therapy or IVIG to prevent bleeding in neonates and morbidity. The commonest maternal risk factors wereAnaemia and Premature ruptureof membrane(PROM). Hence, close monitoring needed if a baby born to mother with additional risk factor.

Keywords : Neonatal Thrombocytopenia, Sepsis, Maternal Anemia, Respiratory Distress Syndrome.

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