Authors :
Dr. Pritam Kumar Sahoo; Dr. Jaya Pandey Mohapatra; Dr. Smruti Dash Mohapatra; Dr. Ipsa Kujur; Dr Manisha Patro; Dr. Jaya Pandey Mohapatra
Volume/Issue :
Volume 7 - 2022, Issue 7 - July
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/3BYYQyt
DOI :
https://doi.org/10.5281/zenodo.6987848
Abstract :
Objective: The objective were to study the causes,
severity and outcome of thrombocytopenia in neonates
admitted to Neonatal Intensive Care Unit in Hi-Tech
Medical College and hospital,Bhubaneswar.
Method: Prospective randomized controlled trial was
done in NICU at Hi-Tech Medical College and Hospital,
Bhubaneswar from September 2019 to August 2021. 100
neonates with or developed neonatal thrombocytopenia
were involved during study.
Result: In this study, out of 100 neonates with
thrombocytopenia- 46%( mild thrombocytopenia ),
35%(moderate thrombocytopenia) and 19%( severe
thrombocytopenia). 51% had(72hr)early onset neonatal
thrombocytopenia and 49% had(72hr)late
onsetneonatal thrombocytopenia. Anaemia was the most
common risk factor found in mother. Sepsis was found
to be commonest cause of thrombocytopenia in neonates.
Apnea was the most common symptom. Sepsis,
Respiratory Distress Syndrome (RDS) and Necrotising
Enterocolitis(NEC) were the cause of mortality.Sepsis
was thecommonest cause of death followed by RDS and
NEC.
Conclusion: In neonates, thrombocytopenia is a treatable
condition. It shouid identify the neonates at risk and
initiate platelet therapy or IVIG to prevent bleeding in
neonates and morbidity. The commonest maternal risk
factors wereAnaemia and Premature ruptureof
membrane(PROM). Hence, close monitoring needed if a
baby born to mother with additional risk factor.
Keywords :
Neonatal Thrombocytopenia, Sepsis, Maternal Anemia, Respiratory Distress Syndrome.
Objective: The objective were to study the causes,
severity and outcome of thrombocytopenia in neonates
admitted to Neonatal Intensive Care Unit in Hi-Tech
Medical College and hospital,Bhubaneswar.
Method: Prospective randomized controlled trial was
done in NICU at Hi-Tech Medical College and Hospital,
Bhubaneswar from September 2019 to August 2021. 100
neonates with or developed neonatal thrombocytopenia
were involved during study.
Result: In this study, out of 100 neonates with
thrombocytopenia- 46%( mild thrombocytopenia ),
35%(moderate thrombocytopenia) and 19%( severe
thrombocytopenia). 51% had(72hr)early onset neonatal
thrombocytopenia and 49% had(72hr)late
onsetneonatal thrombocytopenia. Anaemia was the most
common risk factor found in mother. Sepsis was found
to be commonest cause of thrombocytopenia in neonates.
Apnea was the most common symptom. Sepsis,
Respiratory Distress Syndrome (RDS) and Necrotising
Enterocolitis(NEC) were the cause of mortality.Sepsis
was thecommonest cause of death followed by RDS and
NEC.
Conclusion: In neonates, thrombocytopenia is a treatable
condition. It shouid identify the neonates at risk and
initiate platelet therapy or IVIG to prevent bleeding in
neonates and morbidity. The commonest maternal risk
factors wereAnaemia and Premature ruptureof
membrane(PROM). Hence, close monitoring needed if a
baby born to mother with additional risk factor.
Keywords :
Neonatal Thrombocytopenia, Sepsis, Maternal Anemia, Respiratory Distress Syndrome.
