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Chiari Malformation: A Case Study


Authors : W. Chitra; K. J. Nalini

Volume/Issue : Volume 11 - 2026, Issue 3 - March


Google Scholar : https://tinyurl.com/bd6eub5k

Scribd : https://tinyurl.com/3k5evrvp

DOI : https://doi.org/10.38124/ijisrt/26mar466

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Abstract : Chiari malformation comprises a heterogeneous group of congenital anomalies involving the cerebellum, brainstem, and craniocervical junction, characterized by caudal herniation of cerebellar structures, with or without involvement of the medulla, through the foramen magnum into the spinal canal. These defects are associated with significant perinatal morbidity and mortality, contributing to the burden of congenital anomalies in the community. Early identification through systematic antenatal screening is essential to ensure timely referral, appropriate counselling and continuity of care. Routine prenatal ultrasonography remains a primary, non-invasive modality for early detection, particularly in resourcelimited settings where community health nurses play a pivotal role in antenatal surveillance, risk identification and health education. This case report describes a primigravida at 22 weeks of gestation who presented to an antenatal clinic, where ultrasonography revealed findings suggestive of fetal Chiari malformation. The case underscores the importance of strengthening community-based antenatal services, improving awareness among expectant mothers, and enhancing the role of nursing professionals in early diagnosis and referral systems to reduce adverse fetal outcomes.

References :

  1. Jesus Igor Iruretagoyena Barbara TrampeDinesh Shah (2010). Prenatal diagnosis of Chiari malformation with syringomyelia in the second trimester. Journal of maternal fetal neonatal medicine Feb;23(2):184-6.  doi: 10.3109/14767050903061769.
  2. Mueller DM, Oro' J. (2005) Chiari I malformation with or without syringomyelia and pregnancy: case studies and review of the literature. American  Journal of perinatology  Feb;22(2):67-70
  3. National Institute of Neurological Disorders and Stroke (NINDS) https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Chiari-Malformation-Fact-Sheet, "Chiari Malformation Fact Sheet", NINDS, Publication date June 2017. NIH Publication No. 17-NS-4839
  4. National Institute of Neurological Disorders and Stroke (NINDS) https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Chiari-Malformation-Fact-Sheet, "Chiari Malformation Fact Sheet", NINDS, Publication date June 2017. NIH Publication No. 17-NS-4839
  5. Rebecca C Knickmeyer,1,* Samantha Meltzer-Brody, and et.al (2014). Rate of Chiari I Malformation in Children of Mothers with Depression with and without Prenatal SSRI Exposure. Neuropsychopharmacology. 2014 Oct; 39(11): 2611–2621. Published online 2014 Jun 11. Prepublished online 2014 May 20. doi: 10.1038/npp.2014.114
  6. Sadineni Raghu T, Santh Kumar B, Praful kumar K, Chandra Sekhar K, Chander BN, Boppana Durga Mahita(2017). Prenatal sonographic evaluation of Arnold Chiari II Malformation. International  Journal of Medical  Research Rev 5(01):88-95. doi:10.17511/ijmrr.2017.i01.13

Chiari malformation comprises a heterogeneous group of congenital anomalies involving the cerebellum, brainstem, and craniocervical junction, characterized by caudal herniation of cerebellar structures, with or without involvement of the medulla, through the foramen magnum into the spinal canal. These defects are associated with significant perinatal morbidity and mortality, contributing to the burden of congenital anomalies in the community. Early identification through systematic antenatal screening is essential to ensure timely referral, appropriate counselling and continuity of care. Routine prenatal ultrasonography remains a primary, non-invasive modality for early detection, particularly in resourcelimited settings where community health nurses play a pivotal role in antenatal surveillance, risk identification and health education. This case report describes a primigravida at 22 weeks of gestation who presented to an antenatal clinic, where ultrasonography revealed findings suggestive of fetal Chiari malformation. The case underscores the importance of strengthening community-based antenatal services, improving awareness among expectant mothers, and enhancing the role of nursing professionals in early diagnosis and referral systems to reduce adverse fetal outcomes.

Paper Submission Last Date
31 - March - 2026

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