A study titled “Comparative analysis of Gluteal strengthening exercise and Core Stabilization Exercises program for gluteus dysfunction in chronic low back pain among residence of Ziro, Arunachal Pradesh.” Back ground of the study: Chronic low back pain is the major problem irrespective of age, gender, occupation, and several other factors. The worst consequence of chronic back pain is it reduces work productivity. Surgeries to therapies are the options but all are symptomatic basis. In physiotherapy there are several exercise protocols but there is no clear cut documentation. Objectives of study: To determine the prevalence of gluteus medius weakness and tenderness in people unilateral chronic low back pain. 1. To compare gluteus medius strength and tenderness between symptomatic and asymptomatic side of chronic low back pain. 2. To determine if this gluteus medius strengthening program improved gluteus medius muscle strength. 3. To determine the effectiveness of a gluteus medius strengthening program compared to a standard exercise program in participants with chronic low back pain. Method:The research approach adopted was descriptive and analytical approach. The research design selected for this present study was randomized clinical trial design. The study was conducted at Naturopathy, Yoga, Physiotherapy and life style intervention center of Indira Gandhi technological and medical sciences university, Ziro. 135 clients were identified with chronic low back pain. Based on selection criteria 83 participants were included out of which 34 clients were chosen on conveniences sampling. Data collection procedure:The tool such as manual muscle testing, tenderness points were assessed by therapist as test-retest method and tenderburg sign is an observatory method by three of the therapist independently. SF-36, ODI, FABQ standardized questionnaire were used. content validity of the tool was established by giving to professional experts for translating the questionnaires into local language. Result:The participants were divided into two groups as Group-1: Stabilization exercise program and Group-2: Gluteus medius strengthening group. On evaluating the components we found that Group-2 has good progress in Gluteus medius muscle strength, Significantly reduce in pain as compare to Group-1. Further we found that Both the components of FABQ and SF-36 have been improved significantly in Group-2 as compare to group-1. Surprisingly we got improvement in Oswestry low back pain disability index and 5 times sit to stand test in group-1 as compare to group-2 but statically it is not so significant. Conclusions: The present study indicates that weakness of Gluteus Medius muscle is one of the strong indication for chronic low back pain and strengthening of same muscle can lead to be a one of the best outcome from such pain. Moreover exercises prove again that quality of life can be improved as one of the psychological motivator.